BACKGROUND The 2 × 2 factorial design is widely used for assessing the existence of interaction and the extent of generalizability of two factors where each factor had only two levels. Accordingly, research problems associated with the main effects and interaction effects can be analyzed with the selected linear contrasts. METHODS To correct for the potential heterogeneity of variance structu...

A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturating agent for VST-containing SMEDDS composed of 10% Capmul® MCM, 45% Tween® 20, and 45% Transcutol...

The “Internet of Space Things” (IoST) is an emerging paradigm to provide Internet and data services around the globe. IoST networks can potentially support deployment in underserved areas, such as monitoring inaccessible areas for early warning applications, open ocean sea ice monitoring, surveillance remote ecosystems forests jungles, among others. To enable paradigm, designing developing appr...

The file distribution protocol BitTorrent(BT) is very popular nowadays, and people are used to sharing files with BT clients everyday. In this project, a two factor full factorial design on workloads and BT clients was proposed to test which effect is significant for BT downloading. The first part presents the background knowledge of Peer-to-peer(P2P) and BT and the introduction of several popu...

Two experiments evaluated the self-handicapping hypothesis that alcohol consumption varies directly with individuals' uncertainty of their ability to perform successfully. In a 2 X 2 X 2 factorial design, Experiment 1 manipulated (a) difficulty of an initial intellectual test (insolvable or solvable), (b) feedback regarding test performance (success or none), and (c) instructions regarding the ...

When it is impractical to perform the experimental runs of a fractional factorial design in a completely random order, restrictions on the randomization can be imposed. The resulting design is said to have a split-plot, or nested, error structure. Similarly to fractional factorials, fractional factorial split-plot designs can be ranked by using the aberration criterion.Techniques that generate ...

In Pakistan, mostly flexible pavements are constructed which have a higher susceptibility to rutting, moisture damage and stripping. Under current economic conditions, one such solution overcome this is the addition of economical locally available additives in bitumen being produced by our refineries. This study investigates effects bakelite as an additive on various mechanical properties. Bake...