merican Journal of Audiology • Vol. 24 • 345–348 • September 2015 • Research Forum: Intervention and Outcom p://aja.pubs.asha.org/ by a Univ of Auckland User on 09/30/20 bs.asha.org/ss/rights_and_permissions.aspx Results: Early intervention, either in the form of amplification or cochlear implantation, was associated with higher language scores. Maternal education and communication mode used du...

MicroRNAs (miRNAs) play critical roles in hepatocellular carcinoma (HCC). However, the expression and biological function of miR-345 in HCC remain unknown. The present study demonstrated that miR-345 expression was reduced in HCC tissues and cell lines. Decreased miR-345 expression was associated with unfavorable clinical features and poor prognosis. In vitro functional assays showed that miR-3...

More accurate prediction of the prognosis in women with node-negative breast cancer may improve physicians' ability to identify the patients most likely to benefit from systematic adjuvant therapy. With this in mind, we performed DNA flow-cytometric measurements of ploidy and the fraction of cells in the synthesis phase of the cell cycle (S-phase fraction) on 395 specimens of node-negative brea...

Objective: Deregulation of the cell cycle and apoptosis mechanisms in normal cells causes many problems, including cancer. In this study, a genome-wide expression analysis of cell cycleand apoptosis-related genes in corticosteroid-, vincristine-, and melphalan-resistant U-266 multiple myeloma cell lines was conducted. Materials and Methods: Resistant U-266 sublines were induced by application o...

BACKGROUND Although the initial results of endovascular repair of abdominal aortic aneurysms were promising, current evidence from controlled studies does not convincingly show a reduction in 30-day mortality relative to that achieved with open repair. METHODS We conducted a multicenter, randomized trial comparing open repair with endovascular repair in 345 patients who had received a diagnos...