The Forkhead box M1 (FoxM1) transcription factor is critical for expression of the genes essential for G(1)/S transition and mitotic progression. To explore the cell cycle regulation of FoxM1, we examined the phosphorylation profile of FoxM1. Here, we show that the phosphorylated status and the activity of FoxM1 increase as cells progress from S to G(2)/M phases. Moreover, dephosphorylation of ...

This course prepares students to apply computational approaches to data analysis and visualization to real information from a variety of disciplines and applications. Data visualization is the interactive visual exploration of information using 2-D and 3-D graphics using techniques that highlight patterns and relationships. Data analysis incorporates data management, data transformations, stati...

This course prepares students to apply computational approaches to data analysis and visualization to real information from a variety of disciplines and applications. Data visualization is the interactive visual exploration of information using 2-D and 3-D graphics using techniques that highlight patterns and relationships. Data analysis incorporates data management, data transformations, stati...

Orlistat (Xenical) (Fig. 1), a highly lipophilic tetrahydro derivative of lipstatin, is an inhibitor of gastric and pancreatic lipases required for the hydrolysis of dietary fat (triacylglycerols) in the gastrointestinal tract into free fatty acids and monoacylglycerols. A major contributing factor to the development and maintenance of obesity is excessive intake of dietary triglycerides. Inhib...

A new integer sequence defined on the basis of the EP numbers is introduced (A117570). The EP numbers are defined as ( ) ( )( ) Q P C B A Q Pb Cb Bb Ab x EP n n n + + + + + + + + + + = − − L L 2 1 , where , e non-negative integers and b is the base. We illustrate some general characteristics of EP numbers and the EP sequence. We observe the existence of pairs of consecutive EP numbers (twin EP ...

Comment on: Macurek L, et al. Cell Cycle 2013; 12:251-62.

[This corrects the article on p. 251 in vol. 21, PMID: 26618031.].

Comment on: Macurek L, et al. Cell Cycle 2012; 12:251-62.