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Avril Drummond1† & Lynn Legg2 †Author for correspondence 1Division of Rehabilitation and Ageing, B Floor, Medical School, Queens Medical Centre, Nottingham NG7 2UH, UK Tel.: +44 115 823 0226 Fax: +44 115 823 0231 Avril.Drummond@ nottingham.ac.uk 2Academic Section of Geriatric Medicine, Level 3, Centre Block, Royal Infirmary, Glasgow, UK Tel.: +44 141 211 4953 Fax: +44 141 211 4944 E-mail: step@...
Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of complicated bacteremia (CB) and infective endocarditis (IE). The gold standard treatment for these infections is vancomycin. A vancomycin area under the concentration-time curve from 0 to 24 h (AUC(24))/MIC ratio of >400 has been suggested as a target to achieve clinical effectiveness, and yet to date no study has quantitat...
Background: The observed controversy that N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide (LP-211), a selective serotonin (5-HT7) receptor agonist, may either modify or exacerbate imbalances in serum electrolyte concentrations and renal tissue of spinal cord trauma cases has not been reported yet. The aim of this study was to better understand the effects of a new 5-HT7 receptor a...
Abstract Background A host-protein score (BV) combining the circulating levels of TRAIL, IP-10 and CRP was developed for distinguishing bacterial from viral infection. BV’s potential to impact decision making at emergency department (ED) assessed by comparing BV physician’s etiological suspicion. Methods Rosetta study participants, aged 3 months 18 years with febrile respiratory tract infection...
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