BACKGROUND AND OBJECTIVE Each year millions of Muslims perform pilgrimage to Makkah, Saudi Arabia. It is particularly stressful during the peak five days, when all rituals have to be performed at specific periods of time at different sites. Poor diabetes control in people with diabetes predisposes to morbidity and increases risk of acute complications. We wanted to see how well their blood gluc...

Oscar M. Portilla-Rivera1, Simón J. Téllez-Luis1, José A. Ramírez de León1 and Manuel Vázquez2* Department of Food Science and Technology, UAM Reynosa-Aztlán, Autonomous University of Tamaulipas, Calle 16 y Lago de Chapala s/n, Col. Aztlán, Reynosa, MX-88740 Tamaulipas, Mexico Department of Analytical Chemistry, Veterinary Faculty, University of Santiago de Compostela-Campus de Lugo, ES-27002 L...

Due to the relatively high activity concentrations of (210)Po and (210)Pb that are found in tobacco and its products, cigarette smoking highly increases the internal intake of both radionuclides and their concentrations in the lung tissues. That might contribute significantly to an increase in the internal radiation dose and in the number of instances of lung cancer observed among smokers. Samp...

Housing, Mobility and Unemployment ∗ This paper develops a model that shows why high-skilled workers move more and are therefore unemployed less than low-skilled workers. The model can explain the paradoxical empirical regularity that higher owner-occupation rates are associated with higher levels of unemployment although home-owners tend to be unemployed less. The choice of housing tenure affe...

BACKGROUND In this study, we investigated the functional correlation between microRNA-210 (miR-210) and gene of F-box protein 31 (FBXO31) in regulating breast cancer. METHODS Dual-luciferase assay and quantitative real-time polymerase chain reaction were used to investigate the binding of miR-210 with FBXO31 and their expression patterns in breast cancer. miR-210 was inhibited in breast cance...

Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE). Our recent study demonstrated that the hypoxic-ischemic (HI) treatment significantly increased microRNA-210 (miR-210) in the neonatal rat brain and inhibition of miR-210 provided neuroprotection in ne...

With the emergence of the modern roundabout as an effective form of traffic control in the United States, more and more information is needed when situations arise in which additional traffic control is required. The signalization and metering of roundabouts can relieve congestion during peak hours of the day as well as possibly provide safer access for pedestrians and cyclists. Although the si...

Hanson and Kiparsky (1996, H&K) lay out a formal grammar for Shakespearean iambic pentameter defined by a small set of parameter settings, framed as constraints. In this paper, I investigate the possibility that different sub-genres of Shakespeare’s writing vary, categorically or on a gradient, in their settings for these parameters. To this end, I adapt the still under development Anttila et a...

Hyperlipidemia, including the oxidized low-density lipoprotein (oxLDL) accumulation, is a risk and highly associated with the development of cancers and cardiovascular diseases. microRNA-210 (miR-210), a hypoxia-responsive microRNA regulated by HIF-1α, has been implicated in cancer and cardiovascular disease formation. Furthermore, Bioinformatics analysis revealed that the promoter of the miR-2...

Most metazoan microRNA (miRNA) target sites have perfect pairing to the "seed" sequence, a highly conserved region centering on miRNA nucleotides 2-7. Thus, complementarity to this region is a necessary requirement for target prediction algorithms. However, also non-canonical miRNA binding can confer target regulation. Here, we identified a seedless target of miR-210, a master miRNA of the hypo...