Wetability of biocompatible polymers can be improved by plasma surface modification. The purpose of this study was to surface modify an experimental poly (dimethylsiloxane) rubber (PDMS) material in order to improve its wetability and biocompatibility. Surface properties of the PDMS were characterized using contact angles measurement for wetability analysis. Samples of experimental silico...

Poly(dimethyl siloxane) elastomer, (PDMS) is widely used as a biomaterial. However, PDMS is very hydrophobic and easily colonized by several bacteria and yeasts. Consequently, surface modification has been used to improve its wettability and reduce bacterial adhesion. The aim of this work was to modify the PDMS surface in order to improve its hydrophilicity and bacterial cell repulsion to be us...

A major technical hurdle in microfluidics is the difficulty in achieving high fidelity lithographic patterning on polydimethylsiloxane (PDMS). Here, we report a simple yet highly precise and repeatable PDMS surface micromachining method using direct photolithography followed by reactive ion etching (RIE). Our method to achieve surface patterning of PDMS applied an O2 plasma treatment to PDMS to...

Poly(ethylene glycol) (PEG)/polydimethylsiloxane (PDMS) hydrogels were synthesized by cross-linking norbornene end-functionalized polymers with a tetrafunctional thiol using thiol−norbornene chemistry. The swelling capacity and mechanical properties, including the Young’s modulus (E) and fracture toughness (Gc), of the hydrogels were characterized and quantified as a function of the volume frac...

A major technical hurdle in microfluidics is the difficulty in achieving high fidelity lithographic patterning on polydimethylsiloxane (PDMS). Here, we report a simple yet highly precise and repeatable PDMS surface micromachining method using direct photolithography followed by reactive ion etching (RIE). Our method to achieve surface patterning of PDMS applied an O2 plasma treatment to PDMS to...

The thermo-responsivity of PNIPAAm [poly(N-isopropylcarylamide)]-grafted PDMS [poly(dimethylsiloxane)] surface is a property that could be feasibly used for detaching cells adhered on the surface. We used benzophenone-initiated photopolymerization to graft PNIPAAm on PDMS substrates to construct the PNIPAAm-grafted PDMS surface and this PDMS surface was highly thermo-responsive. hMSCs (human me...

Introduction: Several attempts to invent implantable devices have done, and it is also necessary to develop biocompatible packaging materials for implantable devices. Thus, we evaluated the biocompatibility of polydimethylsiloxane (PDMS) and polymethyl methacrylate (PMMA) by analyzing of the changes of macrophage, macrophage migratory inhibitory factor (MIF) and inflammatory cytokines of the bl...

Introduction: Several attempts to invent implantable devices have done, and it is also necessary to develop biocompatible packaging materials for implantable devices. Thus, we evaluated the biocompatibility of polydimethylsiloxane (PDMS) and polymethyl methacrylate (PMMA) by analyzing of the changes of macrophage, macrophage migratory inhibitory factor (MIF) and inflammatory cytokines of the bl...

Polyimide is one of the most popular substrate materials for the microfabrication of flexible electronics, while polydimethylsiloxane (PDMS) is the most widely used stretchable substrate/encapsulant material. These two polymers are essential in fabricating devices for microfluidics, bioelectronics, and the internet of things; bonding these materials together is a crucial challenge. In this work...