Abstract Background Chronic kidney disease (CKD), especially diabetic CKD, is the condition that most increases risk of lethal coronavirus 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS‑CoV‑2). However, underlying molecular mechanisms are unclear. SARS-CoV-2 and coronavirus-associated receptors factors (SCARFs) regulate cell entry and/or replication. We hypothesized CKD may...

Superoxide dismutase (SOD) as a group of significant and ubiquitous enzymes plays a critical function in plant growth and development. Previously this gene family has been investigated in Arabidopsis and rice; it has not yet been characterized in cotton. In our study, it was the first time for us to perform a genome-wide analysis of SOD gene family in cotton. Our results showed that 10 genes of...

Aux/IAA (Auxin/Indole- 3- Acetic Acid) family, one of the early response gene family auxin signals, is involved in regulating numerous aspects plant growth and development. As an important economic plant, identification  family genes pecan great significance. In this study, a total 37 were identified genome using bioinformatics method, subcellular localization revealed that all its members...

background: catsper genes are a novel family of four sperm-specific calcium channels, which indicate testis-specific expression patterns. despite the crucial role of catsper genes in the male reproduction, very little is known about the factors that regulate their expression. objective: the objective of this study was to investigate the effects of vitamin e treatment on the expression of catspe...

background: bax and bcl-2 are the major members of bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. methods: in this study, the relative level of mrna expression of bax and bcl-2 genes was deter...

Vertebrate akirin genes usually form a family with one-to-three members that regulate gene expression during the innate immune response, carcinogenesis and myogenesis. We recently established that an expanded family of eight akirin genes is conserved across salmonid fish. Here, we measured mRNA levels of the akirin family of Atlantic salmon (Salmo salar L.) during the differentiation of primary...