Polyunsaturated fatty acids (PUFAs) as well as oestrogen (E2) and parathyroid hormone (PTH) affect bone cells. The aim of the study was to determine whether arachidonic acid (AA), E2, and PTH increase prostaglandin E(2) (PGE(2)) synthesis in MG-63 and MC3T3-E1 osteoblastic cells and the level of mediation by COX-1 and COX-2. PGE(2) levels were determined in the conditioned culture media of MG-6...

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The present study aims to discriminate four semi-arid grassland habitats in a Mediterranean Natura 2000 site, Southern Italy, involving 6210/E1.263, 62A0/E1.55, 6220/E1.434 and X/E1.61-E1.C2-E1.C4 (according Annex I of the European Habitat Directive/EUropean Nature Information System (EUNIS) taxonomies). For this purpose, an intra-annual time-series 30 Sentinel-2 images, embedding phenology inf...

Exercise 1 Consider the rolling of two six-sided dice. Let E1 be the event that the dice land on the same number, and E2 the event that their sum is greater than six. 1. What is the size of E2 (i.e how many outcomes does it contain)? 2. What is E1 X E2? 3. What is the size of E1 Y E2? Solution: 1. Let (x, y) denote both the outcome x of the first die and the outcome y of the second. Then E2 = t...

Whereas adenosine itself exerted independent stimulatory and inhibitory effects on the adenylate cyclase activity of a platelet particulate fraction at low and high concentrations respectively, 2-substituted and N6-monosubstituted adenosines had stimulatory but greatly decreased inhibitory effects. Deoxyadenosines, on the other hand, had enhanced inhibitory but no stimulatory effects. The most ...

Cell cycle deregulation and genomic instability play a major role in the aberrant cell proliferation that characterizes tumorigenesis. A novel role of the cyclin e isoform cyclin e2 in these processes is reported in the manuscript " Cyclin e2 induces genomic instability by mechanisms distinct from cyclin e1 " by Caldon et al. 1 in another issue of Cell Cycle, evidence that regulation of cyclin ...

Cell cycle deregulation and genomic instability play a major role in the aberrant cell proliferation that characterizes tumorigenesis. A novel role of the cyclin e isoform cyclin e2 in these processes is reported in the manuscript " Cyclin e2 induces genomic instability by mechanisms distinct from cyclin e1 " by Caldon et al. 1 in another issue of Cell Cycle, evidence that regulation of cyclin ...

A lambda gt11 cDNA library from 10-day-old chicken embryo was screened immunologically using an antiserum against drebrins E1, E2 and A, proteins previously designated S5, S6 and S54, respectively. A cDNA clone for a common domain of drebrin was isolated. Northern blot analysis of chicken brain indicated that drebrin mRNAs are about 2.7 kilobases in molecular size and that expression of these p...

A three-dimensional model of ice Ih based on the fiber bundle approach is presented. A hybrid structure of ice consisting of the oxygen lattice with the P63/mmc crystallographic symmetry and the hydrogen subsystem satisfying the Bernal-Fowler rules is considered. Controllable change of the protons position at hydrogen bounds by optoacoustic perturbation is discussed. Both classic and bispinor H...

Abstract Each Galileo satellite provides coherent navigation signals in four distinct frequency bands. International GNSS Service (IGS) analysis centers (ACs) typically determine products based on the E1/E5a dual-frequency measurements due to software limitation and limited tracking capability of other early time. The goal this contribution is evaluate quality determined by using different (E1/...