AKI YAMADA,1 SUSUMU OHYA,2 MASARU HIRANO,2 MINORU WATANABE,2 MICHAEL P. WALSH,3 AND YUJI IMAIZUMI1 1Department of Pharmacology and Therapeutics and 2Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan; and 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Ca...

Eaton, Philip, Jian-Mei Li, David J. Hearse, and Michael J. Shattock. Formation of 4-hydroxy-2-nonenalmodified proteins in ischemic rat heart. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H935–H943, 1999.—4-Hydroxy-2nonenal (HNE) is a major lipid peroxidation product formed during oxidative stress. Because of its reactivity with nucleophilic compounds, particularly metabolites and proteins co...

Wyman, Bradley T., William C. Hunter, Frits W. Prinzen, and Elliot R. McVeigh. Mapping propagation of mechanical activation in the paced heart with MRI tagging. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H881–H891, 1999.— The temporal evolution of three-dimensional (3-D) strain maps derived from magnetic resonance imaging (MRI) tagging were used to noninvasively evaluate mechanical activati...

Boulton, M., M. Flessner, D. Armstrong, R. Mohamed, J. Hay, and M. Johnston. Contribution of extracranial lymphatics and arachnoid villi to the clearance of a CSF tracer in the rat. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R818–R823, 1999.—The objective of this study was to determine the relative roles of arachnoid villi and cervical lymphatics in the clearance of a cereb...

Farge, Emmanuel, David M. Ojcius, Agathe Subtil, and Alice Dautry-Varsat. Enhancement of endocytosis due to aminophospholipid transport across the plasma membrane of living cells. Am. J. Physiol. 276 (Cell Physiol. 45): C725– C733, 1999.—Formation of intracellular vesicles is initiated by membrane budding. Here we test the hypothesis that the plasma membrane surface area asymmetry could be a dr...

Maréchal, Hervé, Hélene Jammes, Bernard Rossignol, and Philippe Mauduit. EGF precursor mRNA and membrane-associated EGF precursor protein in rat exorbital lacrimal gland. Am. J. Physiol. 276 (Cell Physiol. 45): C734– C746, 1999.—This study was designed to demonstrate the presence of epidermal growth factor (EGF) in the rat exorbital lacrimal gland. EGF precursor gene transcription was demonstra...

Frame, Mary D. S. Conducted signals within arteriolar networks initiated by bioactive amino acids. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1012–H1021, 1999.—Our purpose was to determine the specificity of L-arginine (L-Arg)induced conducted signals for intravs. extracellular actions of L-Arg. Diameter and red blood cell velocities were measured for arterioles [18 6 1.6 (SE) μm] in the c...

CONSUELO PLATA,1 DAVID B. MOUNT,2 VERENA RUBIO,1 STEVEN C. HEBERT,2 AND GERARDO GAMBA1 1Molecular Physiology Unit, Department of Nephrology and Mineral Metabolism, Instituto Nacional de la Nutrición Salvador Zubirán and Department of Medicine, Instituto de Investigaciones Biomédicas, National University of Mexico, Mexico City CP 14000, Mexico; and 2Division of Nephrology, Department of Medicine...