The time histogram method is the most basic tool for capturing a time dependent rate of neuronal spikes. Generally in the neurophysiological literature, the bin size that critically determines the goodness of the fit of the time histogram to the underlying spike rate has been subjectively selected by individual researchers. Here, we propose a method for objectively selecting the bin size from t...

We investigate a spiking neuron model of multisensory integration. Multiple stimuli from different sensory modalities are encoded by a single neural circuit comprised of a multisensory bank of receptive fields in cascade with a population of biophysical spike generators. We demonstrate that stimuli of different dimensions can be faithfully multiplexed and encoded in the spike domain and derive ...

Experimental data have shown that synapses are heterogeneous: different synapses respond with different sequences of amplitudes of postsynaptic responses to the same spike train. Neither the role of synaptic dynamics itself nor the role of the heterogeneity of synaptic dynamics for computations in neural circuits is well understood. We present in this article methods that make it feasible to co...