نتایج جستجو برای: 180 and 136
تعداد نتایج: 16834909 فیلتر نتایج به سال:
We recently demonstrated that polychlorinated biphenyl (PCB) congeners with multiple ortho chlorine substitutions sensitize ryanodine receptors (RyRs), and this activity promotes Ca²⁺-dependent dendritic growth in cultured neurons. Many ortho-substituted congeners display axial chirality, and we previously reported that the chiral congener PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) atropselect...
هدف از پژوهش، بررسی نقش واسطۀ خودکارآمدی تغییر در رابطۀ بین سرمایۀ روانشناختی و تعهد به تغییر کارکنان دانشگاه محقق اردبیلی بود. پژوهش از نظر هدف، کاربردی و از نظر روش، توصیفی از نوع همبستگی بود. با توجه به جدول مورگان و با استفاده از روش تصادفی خوشه‌ای چندمرحلهای، 180 نفر (136 نفر مرد و 44 نفر زن) برای نمونه انتخاب شدند و به پرسشنامۀ سرمایۀ روانشناختی لوتانز، پرسشنامۀ خودکارآمدی تغییر چن، گولی...
SJG-136, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer, is a highly efficient interstrand crosslinking agent that reacts with guanine bases in a 5'-GATC-3' sequence in the DNA minor groove. SJG-136 crosslinks form rapidly and persist compared to those produced by conventional crosslinking agents such as nitrogen mustard, melphalan or cisplatin which bind in the DNA major groove. A panel of Ch...
Chinese hamster and mouse sarcoma 180 ascites cells, treated with high levels of actinomycin D, still carry out limited poly(A) synthesis. The residual activity, which consists of poly(A) chain extension in the cytoplasm as well as in the nucleus, is essentially insensitive to cordycepin. Nuclear polyadenylation proceeds linearly and involves the gradual extension of unusually long poly(A) sequ...
The chromosomal constitutions of four amethopterin-resistant sublines of cultured Sarcoma 180 cells were compared with those of two sensitive sublines. No correlation between amethopterin resistance and chromosomes was observed. The chromosomal character of a resistant subline was completely retained in the sensitive subline derived from it after 9 months of continuous cultivation in the absenc...
The clinical significance of microRNA (miR)‑136‑5p in hepatocellular carcinoma (HCC) has not been verified. Therefore, in the current study, the authors aimed to explore miR‑136‑5p expression and its clinical significance in HCC, as well as to investigate its potential target genes function. The authors detected the levels of miR‑136‑5p in 101 pairs of HCC and para‑cancer tissues via reverse tr...
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