Abstract Colorectal cancer (CRC) is one of the most common malignancies worldwide. Circular RNAs (circRNAs) are involved in pathological processes, especially development cancers, but roles circRNAs CRC largely unknown. In this study, we investigated role and underlying mechanisms Circ_0030998 cell proliferation angiogenesis. We found that was upregulated tissues cells, its upregulation related...

Vascular endothelial growth factors (VEGFs) are the family of extracellular signaling proteins involved in processes angiogenesis. VEGFA overexpression and altered regulation pathways lead to pathological angiogenesis, which contributes progression various diseases, such as age-related macular degeneration cancer. Monoclonal antibodies decoy receptors have been extensively used anti-angiogenic ...