Mice expressing the Torpedo acetylcholine receptor alpha-chain as a neo-self-Ag exhibit a reduced frequency of T cells responding to the immunodominant epitope Talpha146-162 indicating a degree of tolerance. We characterized tolerance induction in these animals by analyzing the residual Talpha146-162-responsive T cell population and comparing it to that of nontransgenic littermates. Using CD4(h...

UNLABELLED Phosphorylation of serines 157, 164, and 172 within the carboxyl-terminal SPRRR motif of the hepatitis B virus (HBV) core (C) protein modulates HBV replication at multiple stages. Threonine 162 and serines 170 and 178, located within the carboxyl-terminal conserved RRRS/T motif of HBV C protein, have been proposed to be protein kinase A phosphorylation sites. However, in vivo phospho...

INTRODUCTION..........................................155 METHODS FOR DETECTING MULTIPLE MOLECULAR FORMS OF AN ENZYME.............155 HEXOKINASE...........................................157 MULTIPLE FORMS OF ENZYMES APPEARING As ARTIFACTS OF PURIFICATION............158 LACTIC DEHYDROGENASE....................................158 ALKALINE PHOSPHATASE....................................161 ESTERA...

The Gen-Probe Aptima human immunodeficiency virus type 1 (HIV-1) RNA assay was adapted for the diagnosis of HIV infection in infants by using dried blood spots. The assay was 99% sensitive (128/129) and 100% specific (162/162). This may prove useful in resource-limited settings, since it precludes the need for a phlebotomist and maintenance of a cold chain.

CONTENTS INTRODUCTION ..... . . ...... ..... ......... .............. . . . ...... .......................... ......................... . . . ... ... 147 ANTIGEN SHARING BETWEEN MICROBES AND THEIR ANIMAL HOSTS .... ... ..... .. 148 Mycoplasma ............................................................. ....... ... ............... ........ ... ......... .. .. 148 Bacteria .........................

B. Tirimula Rao Senior. Assistant professor, Department of Computer Science and Engineering Anil Neerukonda Institute of Technology and Sciences, Sangivalasa, Bheemili Mdl, Visakhapatnam -531 162 B. Sameet, G. Kiran Swathi, K. Vikram Gupta, Ch. RaviTeja, S.Sumana Department of Computer Science and Engineering Anil Neerukonda Institute of Technology and Sciences, Sangivalasa, Bheemili Mdl, Visak...

Department of Allergy and Immunology, Saitama Medical School, Saitama 350-0495; Department of International Affairs and Tropical Medicine, Tokyo Women’s Medical University, School of Medicine, Tokyo 162-8666; Department of Public Health, Kyorin University School of Medicine, Tokyo 181-8611; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan; and Department...