In this study, l-131-MIBG imaging was performed in 44 patients with clinical suspicion of tumors originating from neuro-endocrine system. The patients were referred to our department following plasma and urinary measurement of epinephrine, norepinehrine and vanilmandelic acidfVMA). Radionuclide imaging was performel as a comparative or confirmatory measure in all patients who had previous...

A 65 years old male presented with abdominal pain (R.U.Q) and constipation, associated with weight loss and anorexia since 40 days prior to admission. Serum biochemical tests were normal. Colonoscopy showed hemorrhagic polypoid lesion in the cecum. Barium enema revealed filling defect in the cecum. Sonography revealed a target-shaped lesion (3cm×2.5cm) in upper segment of the right hepati...

OBJECTIVE We assessed the lesion detectability of low-dose diagnostic (123)I-metaiodobenzylguanidine (MIBG) whole-body scans obtained at 6 and 24 h compared with posttreatment (131)I-MIBG whole-body scans in malignant pheochromocytoma and paraganglioma. METHODS Scintigrams obtained in 15 patients with malignant pheochromocytoma and paraganglioma were retrospectively analyzed. Diagnostic scans...

PURPOSE to compare lesion detectability of I-123 MIBG scintigraphy with that of high-dose I-131 MIBG and to evaluate incremental benefit of SPECT/CT over planar image for the detection and localization of the lesions in patients with I-131 MIBG therapy for malignant pheochromocytoma/paraganglioma and neuroblastoma. MATERIALS AND METHODS we retrospectively investigated 16 patients with maligna...

日本アイソトープ協会では1982年から5年ごとに専門委員会を設けて全国核医学診療実態調査を行っており，第9回調査を2022年6月に行った。回答回収率は90％超であった。年間推定検査件数は単光子放出核種を用いた核医学検査が前回より2.7％増加した一方で，PET検査は約1.5％減少した。この結果，核医学検査総数は1.0％増加した。非密封RIを用いた核医学治療は131I-MIBGによる褐色細胞腫・パラガングリオーマや177Lu-ルテチウムオキソドトレオチドによる神経内分泌腫瘍の治療が新規に開始されたが，223Raと131Iを用いた治療件数の減少や一部薬剤の供給停止もあり，全体で17.7％減少した。核医学検査の総数はあまり変わらないが，核医学治療が大きく変化していることが示された。