نتایج جستجو برای: 125 dihydroxy vitamin d3

تعداد نتایج: 140956  

Journal: :The Journal of nutritional biochemistry 2013
Chunxiao Guo Elena Rosoha Malcolm B Lowry Niels Borregaard Adrian F Gombart

The vitamin D receptor (VDR) mediates the pleiotropic biologic effects of 1α,25 dihydroxy-vitamin D3. Recent in vitro studies suggested that curcumin and polyunsaturated fatty acids (PUFAs) also bind to VDR with low affinity. As potential ligands for the VDR, we hypothesized that curcumin and PUFAs would induce expression of known VDR target genes in cells. In this study, we tested whether thes...

Journal: :The Journal of clinical endocrinology and metabolism 2008
Michael F Holick Rachael M Biancuzzo Tai C Chen Ellen K Klein Azzie Young Douglass Bibuld Richard Reitz Wael Salameh Allen Ameri Andrew D Tannenbaum

CONTEXT Two reports suggested that vitamin D2 is less effective than vitamin D3 in maintaining vitamin D status. OBJECTIVE Our objective was to determine whether vitamin D2 was less effective than vitamin D3 in maintaining serum 25-hydroxyvitamin D levels or increased the catabolism of 25-hydroxyvitamin D3. SUBJECTS AND DESIGN This was a randomized, placebo-controlled, double-blinded study ...

Journal: :Annals of the New York Academy of Sciences 2005
Anya M Y Lin K B Chen P L Chao

Antioxidative mechanisms of vitamin D3 were evaluated both in vitro and in vivo. A 4-h incubation of brain homogenates at 37 degrees C increased the formation of Schiff base fluorescent products of malonaldehyde, an indicator of lipid peroxidation. Incubation with vitamin D3 dose-dependently suppressed auto-oxidation. The antioxidative potency for inhibiting zinc-induced lipid peroxidation was ...

استقامتی, علیرضا , زندپارسا, امیرفرهنگ , فریادرس, پارسا , گیلانی لاریمی, ناصر ,

Background: Although a few studies have shown the positive correlation between patients’ serum concentration of 25 OH-Vitamin D3 and type II diabetes mellitus, metabolic syndrome, and insulin resistance, there are controversies regarding the relationship between 25 OH-Vitamin D3 as a risk factor for cardiovascular atherosclerotic diseases that has to be cleared. The aim of this study was to eva...

Journal: :Current eye research 2012
Yanping Lin John L Ubels Mark P Schotanus Zhaohong Yin Victorina Pintea Bruce D Hammock Mitchell A Watsky

PURPOSE This study was designed to measure vitamin D metabolites in the aqueous and vitreous humor and in tear fluid, and to determine if dietary vitamin D3 supplementation affects these levels. We also determined if the corneal epithelium can synthesize vitamin D following UV-B exposure. METHODS Rabbits were fed a control or vitamin D3 supplemented diet. Pilocarpine-stimulated tear fluid was...

Journal: :Menopause 2011
Peter F Schnatz Matthew Nudy David M O'Sullivan Kelly Ethun Susan E Appt Thomas B Clarkson

OBJECTIVE The aim of this study was to investigate the plasma concentrations of vitamin D and its association with plasma lipid profiles. METHODS Plasma vitamin D3 and lipid concentrations were measured in 119 female cynomolgus monkeys (premenopausal, n = 49; ovariectomized, n = 70) consuming approximately 1,000 IU per day of vitamin D3. In a subset of the ovariectomized monkeys (n = 23), vit...

Journal: :iranian journal of basic medical sciences 0
fatemeh faraji immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran maryam rastin immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran fahimeh lavi arab immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad reza kalantari pathology department, ghaem hospital, school of medicine, mashhad university of medical sciences, mashhad, iran shahrzad zamani taghizadeh rabe immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran nafise tabasi immunology research center, buali research institute, school of medicine, mashhad university of medical sciences, mashhad, iran

objective(s): systemic lupus erythematosus (sle) is a multi-factorial autoimmune disease which may be characterized by t lymphocytes dysfunctions. th17 cells have been identified as new effector cells, which play an important role in the pathogenesis. in recent years, immunomodulatory effect of vitamin d3 has been noticed. in the present experiment, the effect of vitamin d3 on the expression of...

Journal: :Lancet 2002
Reinhold Vieth Tanya R Pinto Bajinder S Reen Min M Wong

In June 1999, a 29-year-old man came to the emergency department with right-sided flank pain, conjunctivitis, anorexia, fever, chills, increased thirst, and vomiting. He had lost 5 kg in weight, and was in acute renal failure. He was treated with steroids and discharged. In October, 1999, his 63-year-old father came to the emergency department with similar complaints. He was also in acute renal...

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