The multifunctional factors Imp-a and Imp-b are involved in nuclear protein import, mitotic spindle dynamics, and nuclear membrane formation. Furthermore, each of the three members of the Imp-a family exerts distinct tasksduringdevelopment. InDrosophilamelanogaster, the imp-a2gene is criticalduringoogenesis for ring canal assembly; specific mutations, which allow oogenesis to proceed normally, ...

123I is the most widely used cyclotron-produced radio-halogen in medical research. In this paper, excitation function formulae for nuclear reactions of production are introduced. 124Te (p, 2n)123I and 127I 5n)123Xe → have been studied as a energy neutrons. Both two were created using least squares regression experimental cross sections data, which obtained from Experimental Nuclear Reaction Dat...

two potassium oxalate doped tio2 samples, designated as k1-tio2 and k2-tio2, were synthesized by the base-catalyzed sol-gel process. these samples were impregnated into rubber sheets. two commercial tio2 samples, anatase and degussa p25, were used as reference materials with which the synthesized samples were to be compared. anatase and p25 were also impregnated into rubber sheets and designate...

The Drosophila IMP-L2 gene was identified as a 20-hydroxyecdysone-induced gene encoding a membrane-bound polysomal transcript. IMP-L2 is an apparent secreted member of the immunoglobulin superfamily. We have used deficiencies that remove the IMP-L2 gene to demonstrate that IMP-L2 is essential in Drosophila. The viability of IMP-L2 null zygotes is influenced by maternal IMP-L2. IMP-L2 null proge...

UNLABELLED BACKGROUND Iodine-123-β-CIT, a single-photon emission computed tomography (SPECT) ligand for dopamine transporters (DATs), has been used for in vivo studies in humans, monkeys, and rats but has not yet been used extensively in mice. To validate the imaging and analysis methods for preclinical DAT imaging, wild-type healthy mice were scanned using 123I-β-CIT. METHODS The pharmaco...

We investigated the accuracy of a double-injection method for sequentially measuring cerebral blood flow (CBF) with N-isopropyl-(123I)p-iodoamphetamine (IMP) in simulation studies based on patient data and in clinical studies. The unidirectional clearance of IMP from the blood to the brain (K1; nearly equal to CBF) in the first and second sessions was calculated by means of a microsphere model....

BACKGROUND The impact of increased energy resolution of cadmium-zinc-telluride (CZT) cameras on the assessment of left ventricular function under dual-isotope conditions (99mTc and 123I) remains unknown. The Amsterdam-gated dynamic cardiac phantom (AGATE, Vanderwilt techniques, Boxtel, The Netherlands) was successively filled with a solution of 123I alone, 99mTc alone, and a mixture of 123I and...

Objective(s): Single-photon emission computed tomography (SPECT) using metaiodobenzylguanidine (MIBG) is an important diagnostic tool for the treatment of refractory pheochromocytoma and paraganglioma (PPGL). Owing to the difficulty of SPECT quantification, the tumour-to-background ratio (TBR) is used to assess disease activity. However, the utility of TBR is limited o...

The multifunctional factors Imp-α and Imp-β are involved in nuclear protein import, mitotic spindle dynamics, and nuclear membrane formation. Furthermore, each of the three members of the Imp-α family exerts distinct tasks during development. In Drosophila melanogaster, the imp-α2 gene is critical during oogenesis for ring canal assembly; specific mutations, which allow oogenesis to proceed nor...