To determine the effects of physiological alterations in endogenous angiotensin II activity on basal renal sympathetic nerve activity (RSNA) and its arterial baroreflex regulation, angiotensin II type 1 receptor antagonists were microinjected into the rostral ventrolateral medulla of anesthetized rats consuming a low, normal, or high sodium diet that were instrumented for simultaneous measureme...

Poly-ADP ribose polymerase (PARP) inhibitors are effective for the treatment of BRCA-deficient tumors. Women with these mutations have an increased risk of developing breast cancer and would benefit from effective chemoprevention. This study examines whether the PARP inhibitors, veliparib and olaparib, delay mammary gland tumor development in a BRCA1-deficient (BRCA1(Co/Co);MMTV-Cre;p53(+/-)) m...

The objective of the present experiment was to examine the effect of substituting different quantities of soyabean protein for casein on renal function and lipid metabolism in rats with chronic renal failure induced by a five-sixths nephrectomy. Experimental animals were subjected to a nephrectomy and fed either casein or soyabean protein (200 or 100 g/kg diet). The diets were isoenergetic with...

l-theanine is a water-soluble non-proteinous amino acid mainly found in green tea leaves. Despite the availability of abundant literature on green tea, studies on the use of l-theanine as a feed additive in animals, and especially broilers are limited. The objective of this study was, therefore, to evaluate the effect of different dietary levels of l-theanine on meat quality, growth performance...

Three experiments were conducted to evaluate immune responses in chicks fed fumonisin B1 (FB1). Day-old male chicks were randomly allotted to dietary treatments: 0, 50, 100, or 200 mg FB1/kg diet. In Experiment 1, chicks were fed diets for 3 wk and were injected intravenously with 4.6x10(6) Escherichia coli on Day 21. Blood samples were collected at 60, 120, and 180 min postinjection, and liver...

this study was carried out to evaluate the effect of different levels of essential oils of wormwood (artemisia absinthium) and cumin (cuminum cyminum (on antioxidant status, lipid peroxidation and serum metabolites in broiler chickens for 42 days. 336 day-old male broiler chicks (ross 308) were allocated to 7 treatments with 4 replications .dietary treatments were included a corn-soybean based ...

Under high altitude conditions, the effects of vitamin E (α-tocopherol) on growth performance, intestinal morphology (villus size and type), and absorptive surface area of broiler chickens were evaluated. Chickens were fed diets supplemented with 0, 100, 200 or 400 IU/kg vitamin E for 42 days. On days 14, 28 and 42, birds were sacrificed and three segments of small intestine were dissected. The...

this study was conducted on 24 holstein cows in close-up period, in a split-plot in time design, with a 2×2 factoriel arrangement and in a completely randomized framework to evaluate the effect of pre and postpartum dietary cation-anion differences (dcad) on homeostasis of calcium, acid-base balance and the subsequent lactation performance. the first factor was prepartum dcad for which the anim...

effects of different levels of ascorbic acid consisting of 0, 100, 200, 400, 800 and 1600 mg/kg feed were examined on some immune variables of juvenile great sturgeon (huso huso) weighing 38 g at water temperature 20°c for 16 weeks. significant difference were observed in level of lysozyme in fish treated 400 and 1600 mg compared with control group 8 week post-treatment (p0.05) 16 weeks post-tr...