RESULTSdThe response rate was 53% (258 of 484 eligible). The mean transition age was 19.5 6 2.9 years, and 34% reported a gap .6 months in establishing adult care. Common reasons for transition included feeling too old (44%), pediatric provider suggestion (41%), and college (33%). Less than half received an adult provider recommendation and ,15% reported having a transition preparation visit or...

PROBLEM Early diagnosis of infections with human immunodeficiency virus (HIV) is needed - especially among key populations such as sex workers, transgender people, men who have sex with men and people who use drugs. APPROACH The Brazilian Ministry of Health developed a strategy called Viva Melhor Sabendo ("live better knowing") to increase HIV testing among key populations. In partnership wit...

To detect genomic instability caused by Ac elements in transgenic tomatoes, we used the incompletely dominant mutation Xanthophyllic-1 (Xa-1) as a whole plant marker gene. Xa-1 is located on chromosome 10 and in the heterozygote state causes leaves to be yellow. Transgenic Ac-containing tomato plants which differed in the location and number of their Ac elements were crossed to Xa-1 tester line...

First reported in 1979, anaesthetists now encounter more and more patients with latex allergy. Several risk groups prone to develop this allergy have been identified. A thorough preoperative interview is necessary to detect high-risk patients. For them, the perioperative period is very dangerous because of the many possibilities of contact with latex-containing materials. There is no cure for l...

Human interleukin (IL)-10 is a pleiotropic cytokine acting on a variety of immune cells. Here we show that the protein can be enzymatically iodinated to high specific radioactivity with retention of biological activity. The radiolabeled ligand binds specifically to its receptor in several mouse and human cell lines, notably human B-lymphoma line JY and mouse mast cell line MC/9. Human IL-10 app...