نتایج جستجو برای: 10 and 21

تعداد نتایج: 16974865  

Journal: :Human molecular genetics 2010
Tao Yu Zhongyou Li Zhengping Jia Steven J Clapcote Chunhong Liu Shaomin Li Suhail Asrar Annie Pao Rongqing Chen Ni Fan Sandra Carattini-Rivera Allison R Bechard Shoshana Spring R Mark Henkelman George Stoica Sei-Ichi Matsui Norma J Nowak John C Roder Chu Chen Allan Bradley Y Eugene Yu

Down syndrome (DS) is caused by the presence of an extra copy of human chromosome 21 (Hsa21) and is the most common genetic cause for developmental cognitive disability. The regions on Hsa21 are syntenically conserved with three regions located on mouse chromosome 10 (Mmu10), Mmu16 and Mmu17. In this report, we describe a new mouse model for DS that carries duplications spanning the entire Hsa2...

Journal: :The Journal of Experimental Medicine 1988
S E Ferguson S Rudikoff B A Osborne

Nucleotide sequences of the four genes composing the T15 heavy chain variable region (VH) family of the CBA/J mouse have been determined. Comparison of these sequences with their published BALB/c and C57BL/10 homologues reveals that nucleotide differences found between given alleles of two strains, i.e., CBA/J and BALB/c, are observed in other family members of the same strain. We suggest that ...

2011
Beatriz Almolda Manuela Costa Maria Montoya Berta González Bernardo Castellano

Experimental autoimmune encephalomyelitis (EAE), a well-established model of multiple sclerosis, is characterised by microglial activation and lymphocyte infiltration. Induction of EAE in Lewis rats produces an acute monophasic disease characterised by a single peak of disability followed by a spontaneous and complete recovery and a subsequent tolerance to further immunizations. In the current ...

Journal: :Human molecular genetics 2014
Li Zhang Kai Meng Xiaoling Jiang Chunhong Liu Annie Pao Pavel V Belichenko Alexander M Kleschevnikov Sheena Josselyn Ping Liang Ping Ye William C Mobley Y Eugene Yu

Trisomy 21 (Down syndrome, DS) is the most common genetic cause of developmental cognitive deficits, and the so-called Down syndrome critical region (DSCR) has been proposed as a major determinant of this phenotype. The regions on human chromosome 21 (Hsa21) are syntenically conserved on mouse chromosome 10 (Mmu10), Mmu16 and Mmu17. DSCR is conserved between the Cbr1 and Fam3b genes on Mmu16. T...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم 1390

this work is presented in five parts. in the first part preparation of the starting complex [pt(c^n)cl(dmso)], 1, in which c^n = n(1),c(2?)-chelated, deprotonated 2-phenylpyridine, and dmso = dimethylsulfoxide, and its reaction with 1 equiv of the biphosphine ligands bis(diphenylphosphino)amine, dppa, or bis(diphenylphosphino)methane, dppm, to give the complex [pt(c^n)cl(dppa)], 2, or [pt(c^n)c...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه 1377

‏‎applications such as high definition viedeo reproduction, portable computers, wireless, and multimedia demand, and ever-increasing need for ligh-frequency high-resolution and low-power analog-to-digital converters. flash, two-step flash, and pipeline convertors are fast but consume large amount of power and require large area. to overcome these problems, successive approximation converter blo...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان - دانشکده شیمی 1392

چکیده در بخش اول این پروژه دو روش میکرواستخخرا به نامهای میکرواسخخرا امولسیونی با کمک اموا فراصتتتو 1 و میکرواستتتخخرا مای – مای با کمک هوا 2 ، به عنوان دو روش میکرواستتتخخرا بدون حلال پخشکننده 3 ، برای اسخخرا برخی هیتدروکربتنهای آروماتیتک حلقوی 4 از نمونتههای آبتی بهکار گرفخه و پارامخرهای موثری همچون نوع حلال اسختتتتخرا کننده، حجم حلال اسخخرا کننده، میزان نمک، زمان تابش اموا فراصتو ، تددا...

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