Isocitrate dehydrogenase 1 (IDH1) mutations have been discovered to be frequent and highly conserved in secondary glioblastoma multiforme and lower-grade gliomas. Although IDH1 mutations confer a unique genotype that has been associated with a favorable prognosis, the role of the mutated IDH1 enzyme and its metabolites in tumor initiation and maintenance remains unresolved. However, given that ...

What exactly does “doing conservation” or “incorporating conservation” into ocean science mean? Although today it is often coupled with the sustainable use of natural resources, by definition, conservation traditionally involves the preservation, protection, or restoration of the natural environment or natural ecosystems (Soulé and Wilcox, 1980). In other words, if the conservation intervention...

The growing importance of enterprise risk management and the resulting integration efforts put the need for separate IT risk management frameworks in question. In this research we analyse common and distinct elements of the COSO enterprise risk management and ISACA Risk IT frameworks. The analysis affirms the hypothesis that separate IT risk management frameworks are redundant.