Sir: The structure of the first l8-membered lactone, borrelidin, was described in 1967 by KELLERSCHIERLEIN1). In recent years, four more antibiotics have been added to this class. Concanamycins A, B and C2.3), produced by Streptomyces diastatochromogenes S45, inhibit the proliferation of mouse splenic lymphocytes stimulated by concanavalin A. The fourth antibiotic, virustomycin A4,5) also produ...

Synthetic CpG oligonucleotides are promising components of immunomodulatory drugs for the treatment and prophylaxis infectious diseases, cancers, allergies. Phosphorothioate modification stabilizes these compounds, contributing to achievement a clinical effect, but at same time changes their properties. We used diffusible fluorescent dye dihydroethidium non-diffusible 6-carboxy-2′,7′dihydrochlo...

In this work, we studied the processes of vinyl ester formation by addition benzoic acid to phenylacetylene in presence complex catalysts diacetate-di (2-amino-5-methylthio-1,3,4-thiadiazolo) cobalt(II) ([Co(C3H5N3S2)2(CH3COO)2] and tetrakis(2-amino-5-ethylthio-1,3,4-thiadiazole)-zinc(II) dinitrate ([Zn(C4H7S2)4](NO3)2): 1-phenylvinyl benzoate anti-Markovnikov coupling product - styryl were obt...

UNLABELLED The responses of subjects taking a 20 mg/day lutein diacetate supplement were compared with that for a 20 mg/day crystalline lutein or a placebo. Ten subjects, assigned to each of three groups, lutein diacetate (group 1), lutein (group 2), and a placebo (group 3), were supplemented for 24 weeks. Groups 1 and 2 consumed a dose equivalent to 20 mg per day of free lutein. Serum samples,...

This paper compares the dyeing of cellulose diacetate (cellulose-based) and polyester fabrics using supercritical carbon dioxide (SC-CO2) aqueous media. The benefits in SC-CO2 were clearly demonstrated lab-based pilot-scale studies terms increased colour strength, uniformity, fastness absence auxiliaries such as dispersing agents or surfactants. In addition, “super-levelling” nature medium was ...

A simple and highly efficiently method for the synthesis of 9-aryl-6- (3- methylphenyl)[1,2,4]triazolo [4,3-a]quinolines 8 by oxidation corresponding aryl aldehyde 1-[3-(3-methylphenyl)quinolin-2- yl]hydrazones 7 using iodobenzene diacetate [PhI(OAc)2] in solid state at RT under grinding conditions is described. The yields are very good purity high. structures compounds 3-8 were confirmed their...

Bioplastics are increasingly replacing traditional plastics in many sectors, but the legislative and operative frameworks for their disposal remain unclear: they should be collected treated together with organic fraction of municipal solid waste (OFMSW), often do not biodegrade satisfactorily plants that treat OFMSW. This work focuses on a type cellulose diacetate employed eyewear industry to a...