BACKGROUND We report the synthesis of benzimidazoles using lanthanum chloride as an efficient catalyst. One-pot synthesis of 2-substituted benzimidazole derivatives from o-phenylenediamine and a variety of aldehydes were developed under mild reaction conditions. RESULTS We have examined the effect of different solvents using the same reaction conditions. The yield of the product varied with t...

Dermal exposure to chemicals is highly relevant in relation to the use of cosmetic products, both in consumers and in individuals exposed occupationally. Regulatory frameworks exist within the EU to limit the dermal exposure of the general population and workers to chemicals in general, as well as to limit the use of certain substances in cosmetic products. The objective of the study was to inv...

some new symmetrical tetraaza schiff base ligands containing 2-quinolinecarboxaldehyde moiety formed from condensation reaction of 2-quinolinecarboxaldehyde and o-phenylenediamine derivatives, such as n, nˊ-bis(2-quinolylmethylidene)-4-methoxy-1, 2-phenylenediimine (l1), n, nˊ-bis(2-quinolylmethylidene)-4-methy-1, 2-phenylenediimine (l2), n, nˊ-bis(2-quinolylmethylidene)-4-chloro-1, 2-phenylene...

The carcinogenicity of 23 phenylenediamines and related compounds was reviewed. An extensive analysis of the methods used indicated that the bioassays were conducted well. The data suggest that the carcinogenicity of 4-substituted 1,3-phenylenediamines is reduced substantially or eliminated completely by oxidation of one or both amine groups or by N-substitution. Oxidation of a methyl substitue...

Abstract. The forward osmosis (FO) process has been considered for desalination as a competitive option with respect to the traditional reverse process. interfacial polymerization (IP) reaction between two monomers (i.e., m-phenylenediamine, MPD, and 1,3,5-benzenetricarbonyl chloride, TMC) is typically used prepare selective polyamide layer that prevents salts allows water molecules pass. In th...

Ferricyanide-containing liposomes were used as a system to compare the electron- and proton-translocating properties of six redox reagents commonly used as electron donors for biochemical systems. The effects of different ionophore combinations on the ferricyanide-reduction rate were generally consistent with the expected proton- and electron-translocating properties of the mediators. The trans...

In an innovative approach to push the boundaries of antimicrobial and antioxidant strategies, we present synthesis characterization a novel terpolymer derived from N-Phenyl-p-phenylenediamine 2-aminopyrimidine with formaldehyde in presence dimethylformamide as reaction medium through polycondensation technique. Leveraging this ligand, introduce intriguing terpolymer-metal complex, created Ni (I...

Optimum reaction conditions were evaluated for assay of serum ceruloplasmm by measurement of its p-phenylenediamine oxidase activity. The pH optima of p-phenylenediamine oxidase activities of human and rat ceruloplasmins were 5.45 and 5.2, respectively. The p-phenylenediamine oxidase activity of rat ceruloplasmin was markedly inhibited by phosphate (0.1 mol/Iiter), that of human ceruloplasmin o...

The membrane-bound l-malate oxidoreductase of Azotobacter vinelandii strain O was found to be a flavoprotein-dependent enzyme associated with the electron transport system (R(3)) of this organism. The particulate R(3) fraction, which possessed the l-malate oxidoreductase, carried out the cyanide-sensitive oxidation of l-malate, d-lactate, reduced nicotinamide adenine dinucleotide and nicotinami...