Ryan J R Thompson School of Surveying and Spatial Information Systems, UNSW, Australia Phone (02) 9385 4208 Fax (02) 9313 7493 Email: [email protected] Asghar Tabatabaei Balaei School of Surveying and Spatial Information Systems, UNSW, Australia Phone: (02) 9385 4202 Fax: (02) 9313 7493 Email: [email protected] Andrew G Dempster School of Surveying and Spatial Information Systems, UNSW, ...

In Japanese, Koreans and Caucasians, narcolepsy/hypocretin deficiency is tightly associated with the DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype. Studies in African-Americans suggest a primary effect of DQB1*06:02, but this observation has been difficult to confirm in other populations because of high linkage disequilibrium between DRB1*15:01/3 and DQB1*06:02 in most populations. In this study, ...

The purpose of these studies was to test whether 02 tension influences cardiotoxicity due to doxorubicin. Isolated hearts were perfused by the method of Langendorff at constant pressure with Krebs-Henseleit buffer saturated with 5% CO2 and either 95% or 20% 02. Toxicity due to doxorubicin was evaluated from changes in heart rate and from uptake of trypan blue by nonviable nuclei. Heart rate was...

Multiplex families with type 1 diabetes are important for identification of rare variants that cannot be identified in case-control association studies. The very low incidence of type 1 diabetes in the Japanese population, however, makes identification of such families difficult. We identified a Japanese family in which three members developed type 1 diabetes, and studied the genotype of the hu...

We examined the effect of HLA class I haplotypes on HIV-1 seroconversion and disease progression in the Pumwani sex worker cohort. This study included 595 HIV-1 positive patients and 176 HIV negative individuals. HLA-A, -B, and -C were typed to 4-digit resolution using sequence-based typing method. HLA class I haplotype frequencies were estimated using PyPop 32-0.6.0. The influence of haplotype...