Background: The Canadian Guideline for Parkinson Disease (PD) indicates clozapine and quetiapine are considered the only safe antipsychotics people with PD, to avoid potentially exacerbating motor symptoms. In response safety events in our centre, we explore contraindicated antipsychotic prescriptions being administered hospital inpatients PD determine common factors develop approaches prevent ...

Synthetic cannabinoid drugs do not cross react on traditional marijuana immunoassay tests, preventing their use in large scale drug screening programs. This paper describes the validation and performance characteristics of two enzyme linked immunosorbent assays designed to detect the use of two common synthetic cannabinoids in urine, JWH-018 and JWH-250. The JWH-018 assay has significant cross-...

Abstract Multivitamin tablet certified reference material (CRM, 108-10-019) was developed for the analysis of seven water-soluble vitamins, including thiamine, riboflavin, nicotinamide, pantothenic acid, pyridoxine, biotin, and folic acid. The CRM prepared in powder form by grinding multivitamin tablets then mixing, sieving, bottling powder. For certification each vitamin, isotope dilution mass...

An animal model with a REML algorithm was used to estimate variances of additive genetic effects and interaction effects of sire and herd. Milk and fat yields were analyzed for first, second, and third lactations of Holsteins from California, New York, and Pennsylvania. Twenty samples of data were used in the study: 10 from California, 4 from New York, and 6 from Pennsylvania. Mean number of la...