Graphene (Gr)/metal oxide nanocomposites, as advanced electrode materials, have drawn significant attention in supercapacitors due to their two components' synergistic cooperation, which compensates each other's drawbacks and hence perform better than individual components. In this study, graphene/metal Gr/NiO Gr/Co3O4 binaries were separately synthesized by a co-precipitation method NiO or Co3...

Glucocorticoids play an important biphasic role in modulating neural plasticity; low doses enhance neural plasticity and spatial memory behavior, whereas chronic, higher doses produce inhibition. We found that 3 independent measures of mitochondrial function-mitochondrial oxidation, membrane potential, and mitochondrial calcium holding capacity-were regulated by long-term corticosterone (CORT) ...

Surface modification is a promising approach to modulate the electrocatalyst properties for their further use in energy storage and conversion. In this work, electrochemical-based was proposed generate metallic particles-supported graphite rod (GR). The based on cathodic activation of GR presence alkali metal salts dry organic solvent. activated possess high reducing power that successfully emp...

The management of urinary tract infection (UTI) in individuals with spinal cord injury (SCI) continues to be of concern, due to complications that can occur. An emerging concept that is a common underlying pathophysiological process is involved, wherein pathogens causing UTI have a role in inflammatory progression. We hypothesized that members of the commensal flora, such as lactobacilli, may c...

Zinc oxide (ZnO) is widely incorporated as a food additive in animal diets. In order to optimize the beneficial effects of ZnO and minimize any resultant environmental pollution, ZnO nanoparticles are often used for delivery of the zinc. However, the possible toxic effects of ZnO nanoparticles, including effects on cytochrome P450 (CYP450) enzymes, have not been evaluated. In this study, we inv...

BACKGROUND: Zinc (Zn) is one of the most important essential elements in the body of animals and plants. Zinc plays a significant role in the structure of more than 300 different proteins and in many life supporting biochemical and metabolic processes such as cellular respiration and protection against free radicals. Nanoparticles of zinc are the new form of Zinc used in cosmetic and personal c...

A mechanism-based model for pharmacodynamic effects of dexamethasone (DEX) was incorporated into our model for arthritis disease progression in the rat to aid in identification of the primary factors responsible for edema and bone loss. Collagen-induced arthritis was produced in male Lewis rats after injection of type II porcine collagen. DEX was given subcutaneously in single doses of 0.225 or...

The aryl hydrocarbon receptor (AHR) nuclear translocator (ARNT), as the AHR's heterodimerization partner, and NADPH-cytochrome P450 oxidoreductase (POR), as the key electron donor for all microsomal P450s, are independent and indispensable components in the adaptive and toxic responses to polycyclic aromatic hydrocarbons. Expression of both ARNT and POR in rat liver is induced by dexamethasone ...