1. A simple phosphate infusion technique was employed to produce a linear elevation of plasma phosphorus levels with time. Using this technique theoretical renal phosphorus threshold (TRPT) was determined from sixty-seven infusions performed in fifty subjects in order to evaluate this measure of the renal excretion of phosphorus. 2. Glomerular filtration rate (GFR) was determined from phosphate...

We investigate a model of gate failure for Boolean circuits in which a faulty gate is restricted to output one of its input values. For some types of gates, the model (which we call the short-circuit model of gate failure) is weaker than the traditional von Neumann model where faulty gates always output precisely the wrong value. Our model has the advantage that it allows us to design Boolean c...

Bauer, P. 2017. Parallelism in Event-Based Computations with Applications in Biology. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1586. 48 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0125-9. Event-based models find frequent usage in fields such as computational physics and biology as they may contain both continuous and di...

Prior studies have reported an association between the presence of the 7 repeat allele of the 48 bp repeat polymorphism of the third cytoplasmic loop of the dopamine D4 receptor gene (DRD4) and novelty seeking behaviors, attention deficit hyperactivity disorder (ADHD), Tourette syndrome (TS), pathological gambling, and substance abuse. However, other studies have failed to replicate some of the...

OBJECTIVE We compared associations of epilepsy remission status and severity as well as psychiatric and other comorbidities with child and parent-proxy reports of health-related quality of life (HRQoL) in adolescents previously diagnosed with epilepsy. METHODS In a prospective, community-based study of newly diagnosed childhood epilepsy, HRQoL of 277 children was assessed 8 to 9 years after d...

The gradual decrease in susceptibility of the gonococcus to penicillin has led authorities to recommend ever larger doses for the therapy of gonorrhoea. The current recommendation of the U.S. Public Health Service for the treatment of infections in women is the administration of 4-8 m.u. aqueous procaine penicillin; one half that amount is advised for cases in men. In seeking alternative antibi...

Fatalities from perinatal asphyxia remain high in developing countries, and continually assessing its risk factors will help improve outcomes in these settings. We explored how some identified risk factors predict mortality in asphyxiated newborns, to assist clinicians in prioritizing interventions. This was a 4-year prospective study conducted at the Enugu State University Teaching Hospital, E...

Introduction: Botulinum neurotoxin (BoNT) is probably the most potent biological toxin that can affect humans. Since its discovery by Justinus Kerner, BoNT has seen use in a wide range of cosmetic and non-cosmetic conditions such as cervical dystonia, cerebral palsy, migraines and hyperhidrosis. We tried to trace its history from its inception to its recent urological applications. Materials an...

Objective: In spite of readily available evidence-based guidelines on urolithiasis treatment, practical applications of treatments vary from country to country, or even within countries. The choice of treatment depends not only on the evidence, but often on general non-medical decision factors such as infrastructure, expertise, trends, patient demands, industry drive and reimbursement levels. I...