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Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and 3, leading to acantholysis. The etiology PV multifactorial, including genetic susceptibility. This retrospective study aimed evaluate association HLA class II alleles examine impact PV-associated on concentration anti-d...
Susceptibility to multiple sclerosis (MS) has been linked mainly to the HLA-DRB1 locus, with the HLA-DR15 haplotype (DRB1*1501-DQA1*0102-DQB1*0602-DRB5*0101) dominating MS risk in Caucasians. Although genes in the HLA-II region, particularly DRB1*1501, DQA1*0102-DQB1*0602, are in tight linkage disequilibrium, genome-wide-association, and gene candidate studies identified the DRB1*15:01 allele a...
We prove the following theorem: THEOREM. Let Y be a second countable, infinite R0-space. If there are countably many open sets 01, 02, 0n, in Y such that 01 02 0..., then a topological space X is a Baire space if and only if every mapping f: XY is almost continuous on a dense subset of X. It is an improvement of a theorem due to Lin and Lin [2].
BACKGROUND Co-trimoxazole is a sulfonamide-containing antibiotic that is effective in the treatment of several infections and for prophylaxis of Pneumocystis jiroveci pneumonia. This drug has been reported as a common culprit drug for the Stevens-Johnson syndrome (SJS) and for toxic epidermal necrolysis (TEN). Human leukocyte antigens (HLAs) play a key role in the immunopathogenesis of severe c...
Socioeconomic Status and Life Expectancy in Indiana, 1970-1990~!2010-01-05~!2010-02-01~!2010-04-07~!
Epitopes from all available full-length sequences of yellow fever virus (YFV) and dengue fever virus (DENV) restricted by Human Leukocyte Antigen class I (HLA-I) alleles covering 12 HLA-I supertypes were predicted using the NetCTL algorithm. A subset of 179 predicted YFV and 158 predicted DENV epitopes were selected using the EpiSelect algorithm to allow for optimal coverage of viral strains. T...
SUBJECT: EXTRACORPOREAL SHOCK WAVE THERAPY (ESWT) FOR MUSCULOSKELETAL CONDITIONS AND SOFT TISSUE WOUNDS POLICY NUMBER: 2.01.31 CATEGORY: Technology Assessment EFFECTIVE DATE: 10/18/01 REVISED DATE: 02/21/02, 02/20/03, 02/19/04, 02/17/05, 12/15/05, 01/18/07, 10/18/07, 09/18/08, 08/20/09, 07/15/10, 06/16/11, 06/21/12, 08/15/13, 07/17/14, 06/18/15 PAGE: 1 OF: 8 • If the member's subscriber contrac...
BACKGROUND There are 3 classes of HLA molecules; HLA class I, II and III, of which different classes have different functions. HLA-B gene which belongs to HLA class I play an important role predicting drug hypersensitivity. MATERIALS AND METHODS Nine hundred and eighty-six Thai subjects who registered at a pharmacogenomics laboratory were determined for HLA-B genotype using a two-stage sequen...
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