January 2001 3 This review explores the neurobiology of stress and its possible role in the etiology of schizophrenia. Major life events may play a role in onset and relapse in schizophrenia. Other data suggest that early stress exposure increases schizophrenia risk, especially in individuals with latent vulnerability. Animal research has led to an elucidation of the mechanisms by which stress ...

January 2001 55 n this column, I will discuss the diagnosis, assessment, forensic relevance, and treatment of antisocial personality disorder (APD) and its more severe subtype, psychopathy. In earlier work, I have generally equated the two terms. However, it is now more appropriate to separate them, referring to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)1 to define APD a...