Objectives: To investigate the safety and efficacy of Contractubex® administration to hypertrophic scars in routine out-patient practice and to compare it to corticosteroid treatment. Patients and Methods: This was a multicenter, retrospective cohort study, based on 38 randomly selected practices representatively distributed in Germany, including dermatologists and general practitioners. Data f...

Shortly after the physics Nobel prize award for the invention of the scanning tunneling microscope (STM), Gerd Binnig and Calvin Quate built the atomic force microscope (AFM) in order to avoid the limitations of the STM to image only conductive matter or thin layers of organics (1). Using the miniaturized record player principle similar to a stylus profilometer, it was then possible to image th...

Background and Objectives: Botulinum neurotoxin A (BoNT-A) is the fi rst line treatment for cervical dystonia (CD). Three different preparations are available: abobotulinumtoxinA, onabotulinumtoxinA, and incobotulinumtoxinA. However, potencies between these preparations vary and the products are therefore not easily interchangeable. Methods: We retrospectively compared the treatment plans and o...

In the last few years, galaxies at redshifts up to z ∼ 1 have become accessible for medium–resolved spectroscopy thanks to the new generation of 10m-class telescopes. With kinematic and photometric information on spiral galaxies in this regime, well–known scaling relations like the Tully–Fisher relation (TFR) can be studied over half a Hubble time. By comparison to local samples, these studies ...

INTRODUCTION AND OBJECTIVES Circulating microRNAs (miRNA) are involved in the posttranscriptional regulation of genes associated with lipid metabolism (miRNA-33) and vascular function and angiogenesis (miRNA-126). The objective of this exploratory study was to measure plasma levels of miRNA-33 and miRNA-126 in patients with plaque psoriasis and evaluate their association with clinical parameter...

PURPOSE The present study attempted to identify characteristics that correlated with clinical response to interleukin (IL)-2 therapy in patients with metastatic melanoma. PATIENTS AND METHODS We retrospectively evaluated laboratory and clinical characteristics of 374 consecutive patients with metastatic melanoma treated with high-dose intravenous bolus IL-2 (720,000 IU/kg) from July 1, 1988, ...

Large racial and ethnic differentials in the risk of marital disruption are observed in the United States, with Blacks exhibiting higher rates of disruption than many other groups. We use data from the 1995 National Survey of Family Growth to investigate whether racial/ethnic differences in exposure to risk factors for disruption can explain variation in levels of marital instability across gro...

BACKGROUND AND PURPOSE Endovascular treatment for acute ischemic stroke consists of various mechanical and pharmacologic modalities used for recanalization of arterial occlusions. We performed this study to determine the relationship among procedure time, recanalization, and clinical outcomes in patients with acute ischemic stroke undergoing endovascular treatment. MATERIALS AND METHODS We an...