background: esophageal squamous cell carcinoma (escc) is one of the lethal cancers with a high incidence rate in asia. many genes including cyclin d1 and p16 play important role in its carcinogenesis. we aimed to analyze the expressions of cyclin d1 and p16 with the various clinicopathological characteristics of escc.   method: we examined 30 biopsy samples of escc for cyclin d1 and p16 protein...

Objective(s): Hepatocellular carcinoma (HCC) is one of the most significant health condition around the world. As the only curative therapies, liver transplantation and surgical resection are the clinical treatments of HCC. Due to the systemic toxicity and severe side effects of these treatments, it is vital to establish new therapeutic approaches. The present study ai...

Background & Objective: Glioblastoma-multiforme is the high grade form of astrocytic tumors with a short survival time, which are the most common type of brain tumors. Therefore, finding new therapeutic options is essential. Cyclin D1 is expressed in some human malignancies and can be a potential target for therapeutic intervention. The aim of the present study was to determine...

  Background and Objective: Esophageal cancer especially squamous cell carcinoma (SCC) is one of the most common gastro intestinal malignancies in north part of Iran (Khorasan). The standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. Then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. Sever...

background and objective: esophageal cancer especially squamous cell carcinoma (scc) is one of the most common gastro intestinal malignancies in north part of iran (khorasan). the standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. several ...

This paper is on the normal approximation of singular subspaces when noise matrix has i.i.d. entries. Our contributions are three-fold. First, we derive an explicit representation formula empirical spectral projectors. The neat and holds for deterministic perturbations. Second, calculate expected projection distance between true subspaces. method allows obtaining arbitrary k-th order distance. ...

We reconsider the semileptonic decays of B→D1(′)lν¯l. The previous theoretical calculations predict a significantly smaller rate for decay B to D1′(Jl=12) compared with that D1(Jl=32), which is not consistent current experimental data. This conflict known as so-called ‘12 vs. 32 puzzle’. In this work, we propose simple scheme fix problem, where suppose strong eigenstates D1(′) do coincide eigen...

This work mainly focuses to unveil the optical features of a black hole. For this objective, we utilize metric-affine hole geometry, including dilation, spin, and shear charge. The Lagrangian coefficients f1 d1 are main parameters that differentiate solutions by d1=±8f1, where f1<0. Based on these parameters, carry out in two cases, i.e., d1=8f1,&d1=−8f1. We forecast detailed impact charges pro...