Phospholipase A(1) (PLA(1)) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA(1) enzymes. Where their function is known, PLA(1)s have been shown to act as digestive enzymes, possess central roles in membrane maintenance and remodeling, or r...

Background: There is an ongoing debate about the validity of the A1 criterion of PTSD. Whereas the DSM-5 has opted for a more stringent A1 criterion, the ICD-11 will leave it out as a key criterion. Objective: Here we investigated whether formal DSM-IV-TR traumatic (A1) and stressful (non-A1) events differ with regard to PTSD symptom profiles, and whether there is a gender difference in this re...

The cell plasma membrane contains specialized microdomains called lipid rafts which contain high amounts of sphingolipids and cholesterol. Lipid rafts are involved in a number of membrane protein functions. The urea transporter UT-A1, located in the kidney inner medullary collecting duct (IMCD), is important for urine concentrating ability. In this study, we investigated the possible role of li...

syntax n ∈ Num x ∈ Var a ∈ Aexp a ::= n | x | a1 + a2 | a1 * a2 | a1 a2 Semantic domains Integer = {... -3, -2, -1, 0, 1, 2, 3 ...} Truth-Value = {true, false} State = Var → Integer Semantic valuation functions N: Num → Integer A: Aexp → State → Integer A [[n]] = λs. N [[n]] A [[x]] = λs. s x A [[a1 + a2]] = λs. A [[a1]] s + A [[a2]] s A [[a1 * a2]] = λs. A [[a1]] s * A [[a2]] s 6 Prolog and Au...

For integers a1, . . . , an > 0 and k > 1, let Lk+2(a1, . . . , an) denote the set of permutations of {1, . . . , a1 + · · · + an} whose descent set is contained in {a1, a1 + a2, . . . , a1+ · · ·+an−1}, and which avoids the pattern 12 . . . (k+2). We exhibit some bijections between such sets, most notably showing that #Lk+2(a1, . . . , an) is symmetric in the ai and is in fact Schur-concave. T...

6,463,329 B1 10/2002 Goedeke 6,667,725 B1 12/2003 Simons et al. 2001/0016683 A1 8/2001 Darrow et al. 2002/0027531 A1 3/2002 Brown et al. 2002/0042637 A1 4/2002 Stover 2002/0058906 A1 * 5/2002 Lebel et al. .................. 604/65 2002/0123777 A1 9/2002 Dolgin et al. 2002/0177884 A1 11/2002 Ahn et al. 2005/0267550 A1 * 12/2005 Hess et al. .................... 607/60 6,411,842 B1 * 6/2002 Cigain...

This note investigates πT,c1,c2(a1,a2)=P(supt∈[0,T](σ1B(t)−c1t)>a1,supt∈[0,T](σ2B(t)−c2t)>a2), where {B(t):t≥0} is a standard Brownian motion, with T>0,σ1,σ2>0,c1,c2∈R. We derive explicit formula for the probability πT,c1,c2(a1,a2) and find its asymptotic behavior both in so called many-source high-threshold regimes.

BACKGROUND Macrophage migration inhibitory factor (MIF) is released into the intraluminal fluid during bladder inflammation in the rat complexed to alpha1-inhibitor-3 (A1-I3; a rodent proteinase inhibitor in the alpha-macroglobulin family). The location of A1-I3 in the bladder had not been investigated. Therefore, we examined the location of A1-I3 and MIF/A1-I3 complexes in the bladder and chan...