We propose an integrated modeling, prediction, and analysis framework for the parametric study of the cathode catalyst layer (CCL) of PEM fuel cells. A parametric study is performed on a macro-homogeneous film model of the CCL. An artificial neural network (ANN) is then used in order to model and predict the effect of various structural parameters on the activation overpotential of the CCL. The...

INTRODUCTION Chemokine (C-C motif) ligand 18 (CCL-18) has been shown to be elevated in chronic obstructive pulmonary disease (COPD) patients. This study primarily aimed to evaluate whether the serum CCL-18 level differentiates the frequent exacerbator COPD phenotype from infrequent exacerbators. The secondary aim was to investigate whether serum CCL-18 level is a risk factor for exacerbations r...

Atopic dermatitis (AD) is an inflammatory skin disease in which pathogenesis chemokines are partially involved. The aim of the paper was to assess the serum level of CXCL-9, CXCL-10, CXCL-11, CXCL-12, CCL-17, CCL-20, CCL-21, CCL-22, CCL-27, and IL-18 chosen in AD patients by ELISA assay. Forty patients (mean age 11.4 years old) with AD and 50 healthy controls were enrolled into the study. The p...

Cell-cycle induction in hepatocytes protects from prolonged tissue damage after toxic liver injury. Early growth response (Egr)-1(-/-) mice exhibit increased liver injury after carbon tetrachloride (CCl(4)) exposure and reduced TNF-α production. Because TNF-α is required for prompt cell-cycle induction after liver injury, here, we tested the hypothesis that Egr-1 is required for timely hepatocy...

The therapeutic activities of orally administered FK482 were compared with those of reference antibiotics against systemic and local infections with a variety of bacteria in mice and rabbits. In systemic infections in mice, oral FK482 was almost as effective as oral cefaclor (CCL) and more effective than oral cephalexin (CEX) against Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia...

Ocimum gratissimum (OG) is known as a food spice and traditional herb, which has been recommended for the treatment of various diseases. To investigate the hepatoprotective effect of OG aqueous extract (OGAE), male Wistar rats challenged by carbon tetrachloride (CCl(4)) were used as the animal model of chronic hepatic injury. Significantly increased serum catalase and DPPH levels were detected ...

Liver lymphocytes are enriched in natural killer (NK) cells, and activation of NK cells by injection of polyinosinic-polycytidylic acid (poly I:C) inhibits liver regeneration in the partial hepatectomy model via production of IFN-gamma. However, the role of NK cells in liver regeneration in a model of carbon tetrachloride (CCl(4))-induced liver injury remains unknown. In this study, we investig...

سابقه و هدف: سلامت خاک از مولفه ‏های اصلی در دستیابی به سامانه ‏‏های کشاورزی پایدار بوده که شدت تحت تاثیر عملیات زراعی مانند خاکورزی قرار می ‏گیرد. را توان با استفاده پارامترهای فیزیکی، شیمیایی بیولوژیکی قالب الگوریتم‏ های مشخص کمّی کرد. نتیجه، بررسی وضعیت کیفی باروری مدیریتی مختلف زمین جهت استقرار مناسب برای تولید بهینه نظام‌های امری ضروری می‏ باشد. چارچوب ارزیابی مدیریت SMAF 1 عنوان ابزاری قدر...