SUMO is a posttranslational modifier that can modulate protein activities, interactions, and localizations. As the GFP-Smt3p fusion protein has a preference for subnucleolar localization, especially when deconjugation is impaired, the nucleolar role of SUMO can be the key to its biological functions. Using conditional triple SUMO E3 mutants, we show that defects in sumoylation impair rDNA maint...

Half-smooth tongue sole (Cynoglossus semilaevis) is an important aquaculture flatfish in China. Cytogenetic analysis has revealed that its sex determination system is female heterogametic (ZZ/ZW). The W chromosome is morphologically larger and has been considered evolutionarily younger than any other chromosome in the set. However, the genetic origin and evolution process of this neo-chromosome...

bipolaris oryzae causes rice brown spot disease which reduces rice yield with substantial global impact. streptomycetes isolated from rice fields of guilan province, iran, showed antifungal activity against the tested pathogen. from five active streptomyces spp. isolates, isolate g showed high antagonistic activity. to determine its taxonomical identity, its colonies characterized morphological...

Black yeasts morphologically identified as Exophiala cf. spinifera were re-analyzed on the basis of morphology, nutritional physiology and ITS rDNA sequencing data. Ribosomal small subunit (SSU) DNA sequence data confirmed that strains belonged to a clade containing the ex-type strain of E. spinifera. Variation in the Internal Transcribed Spacer (ITS) region of the rDNA was studied within this ...

conclusions the widespread distribution of l. major parasites in human suggests not only t. indica was the main reservoir but also other rodents and mammalian hosts might be the reservoir hosts of zcl in the region. molecular and phylogenetic analyses confirmed the strength of haplotype variation maintaining the circulation of leishmania species in their reservoir hosts. results leishmania majo...