نتایج جستجو برای: ژن axin2

تعداد نتایج: 16196  

Journal: :Mechanisms of Development 2009
M. Angeles Rabadán Jordi Cayuso Catarina Cruz James Briscoe Elisa Martí

Axin2 loss, we are over-expressing a drug-stabilised b-catenin construct in wild-type skull osteoblast cultures, and in skull explant (calvarial) cultures. Using a drug-dependent b-catenin will allow us to investigate the threshold levels of Wnt signalling required for ossification and the stages at which the b-catenin signal is critical for osteoblast differentiation. Our findings from these i...

Journal: :Mechanisms of Development 2009
Michaela Mai Oliver Dittrich-Breiholz Michael Kracht Achim Gossler

Axin2 loss, we are over-expressing a drug-stabilised b-catenin construct in wild-type skull osteoblast cultures, and in skull explant (calvarial) cultures. Using a drug-dependent b-catenin will allow us to investigate the threshold levels of Wnt signalling required for ossification and the stages at which the b-catenin signal is critical for osteoblast differentiation. Our findings from these i...

Journal: :Investigative Opthalmology & Visual Science 2016

2017
Yukihiro Saito Kazufumi Nakamura Daiji Miura Kei Yunoki Toru Miyoshi Masashi Yoshida Norifumi Kawakita Tomonari Kimura Megumi Kondo Toshihiro Sarashina Satoshi Akagi Atsuyuki Watanabe Nobuhiro Nishii Hiroshi Morita Hiroshi Ito

Vascular medial calcification is often observed in patients with arteriosclerosis. It is also associated with systolic hypertension, wide pulse pressure, and fluctuation of blood pressure, which results in cardiovascular events. Eicosapentaenoic acid (EPA) has been shown to suppress vascular calcification in previous animal experiments. We investigated the inhibitory effects of EPA on Wnt signa...

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