Tanshinone IIA (Tan II A) is widely used in the treatment of cardiovascular diseases as an active component of Salvia miltiorrhiza Bunge. It has been demonstrated to have pleiotropic effects for atherosclerosis. From the anti-inflammatory and immunomodulatory mechanism perspective, this paper reviewed major progresses of Tan IIA in antiatherosclerosis research, including immune cells, antigens,...

In this survey, the chromosome counts of eight Nepeta L. species were investigated and karyotypic diversity among these was studied. The examined belong to N. cephalotes Boiss. group, namely eremokosmos Rech.f., gloeocephala Rech. f., Boiss., pungens (Bunge) Benth., ispahanica mahanensis Jamzad & Simonds, hormozganica denudata Benth. collected from different habitats in Iran. ploidy levels,...

BACKGROUND Jiangtang decoction (JTD) is a China patented drug which contains Euphorbia humifusa Willd, Salvia miltiorrhiza Bunge, Astragalus mongholicus Bunge, Anemarrhena asphodeloides Bunge, and Coptis chinensis Franch. For decades, it has also been used clinically to treat diabetic nephropathy (DN) effectively; however, the associated mechanisms remain unknown. Thus, the present study aimed ...

In einer Reihe von Untersuchungen wird die philosophische Disziplin der Ontologie als Grundlage für die Informationsmodellierung verwendet. Aufbauend auf der Bunge-Ontologie wird in diesem Beitrag eine Vorgehensweise zur ontologischen Evaluierung von Referenzmodellen präsentiert und anhand des YCIM-Modells von Scheer exemplarisch angewendet.

Background. Insulin resistance (IR) is the main etiology of type 2 diabetes mellitus (T2DM). It has been known that total flavonoid extracts can markedly improve the hypoglycemic symptoms caused by IR. Nevertheless, the relevant molecular mechanism remains unclarified. Aim. This study aimed to investigate the antihyperglycemic effects and mechanism of the total flavonoid extract from Oxytropis ...

To establish an HPLC method for determination of tanshinone IIA in Salvia miltiorrhiza Bunge extract, and observe the protective effect of Salvia miltiorrhiza extract on myocardial ischemia-reperfusion injury in rats. Column used is a Diamonsil C18, mobile phase is methanol-water (75:25), and detection wavelength is 270 nm. Ischemia-reperfusion injury model is replicated, and the size of myocar...