نتایج جستجو برای: پوششهای rtv
تعداد نتایج: 697 فیلتر نتایج به سال:
BACKGROUND HIV and malaria geographically overlap. HIV protease inhibitors kill malaria parasites in vitro and in vivo, but further evaluation in clinical studies is needed. METHODS Thirty-one children from Malawi aged 4-62 months were followed every 3 months and at intercurrent illness visits for ≤47 months (September 2009-December 2011). We compared malaria parasite carriage by blood smear ...
در این مطالعه پوششهای کربنات ثانویه در مقاطع نازک خاکهای منطقه تاکستان مورد بررسی قرار گرفته است. بر اساس نقشه‌های توپوگرافی و مشاهدات صحرایی اولیه، ترانسکتی متشکل از 10 پروفیل خاک انتخاب گردید. این پروفیلها طبق استانداردهای USDA تشریح و نمونه‌برداری شدند. نمونه‌های دست‌خورده مورد تجزیه‌های فیزیکوشیمیای قرار گرفتند و مقاطع نازک نیز از نمونه‌های دست‌نخورده و جهت‌دار تهیه شدند. بر اساس مطالعات می...
This article is to provide an update overview of cobicistat (COBI)-boosted darunavir in response to its recent approval by the US Food and Drug Administration, and inclusion as an alternative first-line regime in the 2015 treatment guidelines in the US. COBI is a relatively new non-antiretroviral cytochrome P450 3A inhibitor or pharmacoenhancer. The rationale behind COBI development was to prov...
A number of secondary plant metabolites (e.g., flavonoids) possess antiviral/antimicrobial activity. Most flavonoids, however, are difficult to study, as they are immiscible in water-based systems. The relatively new semisynthetic α-glucosyl hesperitin (GH), and the natural plant product epigallocatechin gallate (EGCG) are unique among most flavonoids, as these flavonoids are highly soluble. Th...
OBJECTIVES To compare the response to ritonavir (RTV) plus saquinavir (SQV) with single protease inhibitor (PI) therapies among PI-naive HIV-1 infected individuals. METHODS Response to treatment was analysed according to the intent-to-treat principle in a prospective observational cohort study of 177 patients who between May 1995 and March 2000 started a double PI therapy with RTV and SQV (no...
OBJECTIVE AND DESIGN Treatment of human immunodeficiency virus (HIV)-infected women with the highly active antiretroviral therapy (HAART) has reduced the onset of uterine cervical intraepithelial neoplasia (CIN), and halted its progression to cervical carcinoma. We and others demonstrated that the HIV protease inhibitors (HIV-PIs) used in HAART can exert direct antitumour activities also in HIV...
Results Patient 1 is 57 year old HIV+ male (CDC C3), first diagnosed in 1990, who has been on various antiretroviral regimens since 1992. He presented with a VL of 72.551 copies/mL, 56 CD4 cells/mm and candida esophagitis. HAART was initiated with DRV/RTV 600/100 mg in combination with etravirine (ETR) and raltegravir (RAL). DRV and RAL tablets were crushed, ETR was suspended and ritonavir (RTV...
BACKGROUND This study aimed to evaluate whether low darunavir (DRV) minimum plasma concentration (Cmin) values contribute to virological outcomes during DRV/ritonavir monotherapy (mtDRV/rtv). METHODS This was a prospective observational single-arm 96-week efficacy study in virologically suppressed subjects on triple therapy switched to mtDRV/rtv (800/100 mg every 24 h). Previous virological f...
AIM The purpose of this study was to assess the difference of removal torque values (RTV) and the bone-to-implant contact (BIC) between the sand-blasted, large grit, and acid-etched (SLA) surface-treated and the machined surface (MA) miniscrews. MATERIAL AND METHODS Miniscrews used in this study were 6mm long with a diameter of 1.5mm. A total of 23 SLA miniscrews and 24 MA miniscrews were pla...
Transmissible vaccines have the potential to revolutionize infectious disease control by reducing the vaccination effort required to protect a population against a disease. Recent efforts to develop transmissible vaccines focus on recombinant transmissible vaccine designs (RTVs) because they pose reduced risk if intra-host evolution causes the vaccine to revert to its vector form. However, the ...
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