Background: Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been directly associated with inflammation and the production of free radicals are the prostaglandin 13,14-dihydro 15-keto PGF2α and the isoprostane 8-iso-PGF2α. Results: To further delineate the role of inflamma...

the aim of this study was to determine the effects of ecg, pgf2α and gnrh hormone on improvement of reproduction performance of cidr synchronized zandi ewes in breeding season. 500 ewes with age of 2.5-4 years and same nutritional condition were selected for this study and received cidr for 12 days. then these ewes were assigned to five equal groups. first group received no hormone (control gro...

This study compared the therapeutic efficacy of levofloxacin, ornidazole and alpha tocopherol combination and prostaglandin F2α (PGF2α) in longstanding cases of endometritis and evaluated their impact on Interleukin-6 (IL-6) and Interleukin-10 (IL-10) transcript level in peripheral blood leukocytes. Eighteen endometritic crossbred Jersey cows were randomly al...

the objective of this study was to evaluate three methods of estrous synchronization, viz. controlled internal drug releasing device (cidr), intravaginal sponges impregnated with fluogestone acetate (fga), and cloprostenol (estrumate; an analogue of prostaglandin f2α) in nadooshani goats of yazd province, iran.the estrous synchronized does (n = 30 to 33 per treatment), after heat detection, wer...

the aim of this study was to evaluate the effect of ecg, pgf2α, and combination of ecg and pgf2α early postpartum on reproductive performance in high producing dairy cows. three hundred sixty eight postpartal holstein dairy cows were divided in 4 groups. cows in groups 1 and 2 received 500 iu ecg on day 8 ± 2 and cows in groups 3 and 4 received saline. cows in groups 1 and 3 received injections...

The roles of oxidative stress on nuclear factor (NF)‑κB activity and cardiomyocyte apoptosis during heart failure were examined using the antioxidant N‑acetylcysteine (NAC). Heart failure was established in Japanese white rabbits with intravenous injections of doxorubicin, with ten rabbits serving as a control group. Of the rabbits with heart failure, 12 were not treated (HF group) and 13 recei...

BACKGROUND Chronic oxidative stress is one of the key mechanisms responsible for disease progression in non-alcoholic fatty liver disease. However, so far, few studies reported increased circulating levels of oxidative stress markers in patients with non-alcoholic fatty liver and no study has been performed with newer markers of systemic oxidative stress. The aim was to assess the relationship ...