OBJECTIVE To evaluate the accuracy of a smartphone application measuring heart rates (HRs), during an exercise and discussed clinical potential of the smartphone application for cardiac rehabilitation exercise programs. METHODS Patients with heart disease (14 with myocardial infarction, 2 with angina pectoris) were recruited. Exercise protocol was comprised of a resting stage, Bruce stage II,...

BACKGROUND Exercise testing in children is widely recommended for a number of clinical and prescriptive reasons. Many institutions continue to use the Bruce protocol for treadmill testing; however, with its incremental changes in speed and grade, it has challenges for practical application in children. We have developed a novel institutional protocol (British Columbia Children's Hospital (BCCH)...

Treadmill tests for maximal oxygen uptake (V̇O2max) have traditionally used set speed and incline increments regardless of participants training or exercise background. The aim of this study was to determine the validity of a novel athlete-led protocol for determining maximal aerobic fitness in adults. Twenty-nine participants (21 male, 8 female, age 29.8 ± 9.5 y, BMI 24.4 ± 3.1, mean ± SD) from...

Surgeon-Captain David Bruce (1855-1931) (ANONYMOUS, 1931a, 1931b, 1932; HAMERTON, 1932; J. R. B., 1932) was posted to Pietermaritzburg, Natal, South Africa, for military field service in 1894. At the time, cattle (and also horses) were dying in hundreds from a disease the origin(s) of which was obscure; the Zulus gave it the name nagana (MACARTHUR, 1955). As a result, the country was faced with...

Baculoviral inhibitor of apoptosis repeat-containing (Birc)6 gene/BIRC6 (Bruce/APOLLON) encodes an inhibitor of apoptosis and a chimeric E2/E3 ubiquitin ligase in mammals. The physiological role of Bruce in antiapoptosis is unknown. Here, we show that deletion of the C-terminal half of Bruce, including the UBC domain, causes activation of caspases and apoptosis in the placenta and yolk sac, lea...

1. Beeson, P. B. and Hoagland, C. L.: Use of calcium chloride in relief of chills following serum administration. Proc. Soc. exp. Biol. (N. Y.), 1938, 38, 160-162. 2. Hoagland, C. L., Beeson, P. B., and Goebel, W. F.: The capsular polysaccharide of the Type XIV pneumococcus and its relationship to the specific substances of human blood. Science, 1938, 88, 261-263. 3. MacLeod, C. M., Hoagland, C...