AIMS To establish normative data for phalangeal quantitative ultrasound (QUS) measures in Brazilian students. METHODS The sample was composed of 6870 students (3688 females and 3182 males), aged 6 to 17 years. The bone status parameter, Amplitude Dependent Speed of Sound (AD-SoS) was assessed by QUS of the phalanges using DBM Sonic BP (IGEA, Carpi, Italy) equipment. Skin color was obtained by...

The SOS response is an important mechanism which allows Escherichia coli cells to maintain genome integrity. Two key proteins in SOS regulation are LexA (repressor) and RecA (coprotease). The signal for SOS induction is generated at the level of a RecA filament. Depending on the type of DNA damage, a RecA filament is produced by specific activities (helicase, nuclease and RecA loading) of eithe...

While Ras activation has been shown to play an important role in signal transduction by the T-lymphocyte antigen receptor, the mechanism of its activation in T cells is unclear. Membrane localization of the guanine nucleotide exchange factor Sos, but not Vav or Dbl, was sufficient for Ras-mediated signaling in T lymphocytes. Activation of Sos appears to involve membrane recruitment and not allo...

One of the primary challenges for decision makers during concept exploration in engineering system design is selecting designs that are valuable throughout the operational lifetime of the system. The problem is even more difficult when designing Systems of Systems (SoS), which are dynamic, complex, higher-order systems that may be composed of both legacy and new component systems. There are sev...

Satellite remote sensing of plant phenology provides an important indicator of climate change. However, start of the growing season (SOS) estimates in Northern Hemisphere boreal forest areas are known to be challenged by the presence of seasonal snow cover and limited seasonality in the greenness signal for evergreen needleleaf forests, which can both bias and impede trend estimates of SOS. The...

Escherichia coli cells have multiple mutagenic pathways that are induced in response to environmental and physiological stimuli. Unlike the well-investigated classical SOS response, little is known about newly recognized pathways such as the UVM (UV modulation of mutagenesis) response. In this study, we compared the contributions of the SOS and UVM pathways on mutation fixation at two represent...

The unitary representation of exact quantum Poincaré mapping is constructed. It is equivalent to the compact representation [19, 22, 23] in a sense that it yields equivalent quantization condition with important advantage over the compact version: since it preserves the probability it can be literally interpreted as the quantum Poincaré mapping which generates quantum time evolution at fixed en...

A System of Systems (SoS) is an arrangement of useful and independent complex systems, which are integrated into a bigger system that delivers unique capabilities [1]. In this context, it is important to notice that each independent system should be capable of operate and fulfil useful purposes on its own environment, but, when these independent systems are together and become a SoS they are ab...

Effect-directed analysis (EDA) was performed to identify the major aryl hydrocarbon receptor (AhR) agonists in sediments collected from a highly industrialized area (Lake Shihwa, Korea). Great AhR-mediated potencies were found in fractions containing aromatic compounds with log Kow values of 5-8, and relatively great concentrations of styrene oligomers (SOs) and polycyclic aromatic hydrocarbons...