نتایج جستجو برای: میکرو rnas

تعداد نتایج: 38119  

Journal: :The Journal of Cell Biology 2002
Helge Grosshans Frank J. Slack

Two small temporally regulated RNAs (stRNAs)* of approximately 22 nucleotides regulate timing of gene expression during development of the nematode C. elegans. This regulation occurs at a posttranscriptional, presumably translational, level and is distinct from RNA interference (RNAi). One of the two stRNAs, let-7, as well as its target gene, lin-41, are highly conserved even in humans, suggest...

Journal: :Annals of palliative medicine 2021

Background: This study sought to identify the circular RNAs (circRNAs) differentially expressed in oral lichen planus (OLP) investigate possible role of circRNAs this disease’s pathogenesis.

2017
Eric Mick Ravi Shah Kahraman Tanriverdi Venkatesh Murthy Mark Gerstein Joel Rozowsky Robert Kitchen Martin G. Larson Daniel Levy Jane E. Freedman

BACKGROUND AND PURPOSE There is increasing interest in extracellular RNAs (ex-RNAs), with numerous reports of associations between selected microRNAs (miRNAs) and a variety of cardiovascular disease phenotypes. Previous studies of ex-RNAs in relation to risk for cardiovascular disease have investigated small numbers of patients and assayed only candidate miRNAs. No human studies have investigat...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Natalia G Starostina Sarah Marshburn L Steven Johnson Sean R Eddy Rebecca M Terns Michael P Terns

Box C/D RNAs are small, noncoding RNAs that function in RNA modification in eukaryotes and archaea. Here, we report that box C/D RNAs exist in the rare biological form of RNA circles in the hyperthermophilic archaeon Pyrococcus furiosus. Northern analysis of box C/D RNAs reveals two prominent RNA species of different electrophoretic mobilities in total P. furiosus RNA preparations. Together, th...

2012
Anandwardhan A. Hardikar Michael D. Walker Francis Lynn

Recent years have witnessed many remarkable discoveries in the life sciences that have led to major paradigm shifts. An example is the emerging appreciation of the critical role of noncoding RNAs in a broad range of physiological and pathological processes. One such class of noncoding RNAs, the microRNAs (miRNAs), controls intricate networks of gene expression via post-transcriptional mechanism...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه - دانشکده فنی 1391

این پایان نامه به بررسی اثرات پارامتر مقیاس طول روی پایداری و فرکانس اصلی میکرو صفحات مستطیلی و دایره ای می پردازد که در دستگاه های rf mems کاربرد دارند. با استفاده از تئوری تنش کوپل پیراسته، معادلات حاکم بر میکرو صفحات کیرشهف و میندلین با تحریک الکترو استاتیکی استخراج می شوند. محدوده ی پایداری میکرو صفحات بر پایه ی تئوری تنش کوپل پیراسته تعیین شده و با مقادیر به دست آمده از تئوری کلاسیک مقایسه...

Objective(s): Recent progress in understanding the pathogenesis of premature ventricular contraction (PVC)-induced cardiomyopathy (PIC) has suggested a key role for inflammation. The aim of this study was to evaluate the expression of messenger RNAs (mRNAs) and the protein production of interleukin-6 (IL-6), IL-10, tumor necrosis factor alpha (TNF-α) and interferon-γ (...

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