Performance of low temperature fuel cells depends critically on the nanostructures of the material components in the electrodes and membranes. Some studies are reported here for 1) mixed metal nanoparticles supported on mesoporous carbon and 2) modification of nanopores of Nafion via in-situ polymerization of furfuryl alcohol. The anodic oxidation of small organic molecules such as alcohols in ...

Murine monoclonal antibody (mAb) Lym-1 is an immunoglobulin G2a specific for certain human leukocyte antigen-DR variants expressed on the surface of malignant B cells. It has been proposed for serotherapy in patients with B lymphomas. We have previously shown that mAb Lym-1 synergizes with granulocyte macrophagecolony stimulating factor to promote Raji B-lymphoid cell lysis by human neutrophils...

Organic carbonyl electrode materials of lithium batteries have shown multifunctional molecule design and high capacity, but have the problems of poor cycling and low rate performance due to their high solubility in traditional carbonate-based electrolytes and low conductivity. High-performance organic lithium batteries with modified ether-based electrolyte (2 m LiN(CF3SO2)2 in 1,3-dioxolane/dim...

The adaptor protein, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), connects pathogen/danger sensors such as NLRP3 and NLRC4 with caspases and is involved in inflammation and cell death. We have found that ASC activation induced caspase-8-dependent apoptosis or CA-074Me (cathepsin B inhibitor)-inhibitable necrosis depending on the cell type. Unlike necrop...

The aim of this study was to determine which endothelial factors were involved in the decrease of pulmonary vascular resistance at birth, and how they changed with maturation. Response of intrapulmonary artery rings precontracted with prostaglandin F2alpha were studied from piglets aged <2 h, 2-3 day, 10 day and adult pigs for pharmacological responses to acetylcholine (ACh) and cromakalim (CMK...

Ordered mesoporous carbon (CMK-3) with different surface modifications is applied as a support for Fe-based catalysts in the Fischer-Tropsch to olefins synthesis (FTO) with and without sodium and sulfur promoters. Different concentrations of functional groups do not affect the size (3-5 nm) of Fe particles in the fresh catalysts but iron (carbide) supported on N-enriched CMK-3 and a support wit...

Down syndrome children with acute megakaryocytic leukemia (AMkL) have higher cure rates than non-Down syndrome acute myeloid leukemia (AML) patients treated with cytosine arabinoside (ara-C). Megakaryoblasts from Down syndrome AML patients are more sensitive in vitro to ara-C than cells from non-Down syndrome AML patients. Somatic mutations in the GATA1 transcription factor have been detected e...

Activation of the mitogen-activated protein (MAP) kinase pathway has been associated with both cell proliferation and differentiation. Constitutively activated forms of Mek (MAP kinase/Erk kinase) and Erk (MAP kinase) have been previously shown capable of inducing differentiation or proliferation in nonhematopoietic cells. To specifically examine the role of Erk activation in megakaryocytic gro...