نتایج جستجو برای: مراکز dic

تعداد نتایج: 26159  

2015
Manzhi Wang Haiming Kou Jun Deng Huafang Wang Tao Guo Heng Mei Yu Hu Gangjian Qin

OBJECTIVES To retrospectively validate the new Chinese DIC scoring system (CDSS). METHODS This study retrospectively collected the information of 619 patients (371 cases with non-hematologic malignancies, 248 cases with hematologic malignancies) who suspected of DIC in Wuhan Union Hospital during 2013-4 to 2014-6. We validated CDSS by comparing it with three leading scoring systems, from Inte...

2013
Ryuji Ohashi Yusuke Hosokawa Go Kimura Yukihiro Kondo Keiji Tanaka Shinichi Tsuchiya

Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder in patients with prostate cancer. However, renal involvement in DIC associated with prostate cancer has rarely been documented. Herein, we present a case of metastatic prostate cancer presenting with acute renal failure (RF) triggered by DIC. An 80 year old man with metastatic prostate cancer was treated with...

2011
Erik Sundberg Johan Hultdin Sofie Nilsson Clas Ahlm

BACKGROUND Viral hemorrhagic fevers (VHF) are considered to be a serious threat to public health worldwide with up to 100 million cases annually. The general hypothesis is that disseminated intravascular coagulation (DIC) is an important part of the pathogenesis. The study objectives were to study the variability of DIC in consecutive patients with acute hemorrhagic fever with renal syndrome (H...

Journal: :Seminars in thrombosis and hemostasis 2001
R M Hardaway C H Williams Y Vasquez

Disseminated intravascular coagulation (DIC) has been considered a rather rare syndrome characterized by severe bleeding. In fact, both of these beliefs are wrong. Bleeding is fairly rare in DIC. The clotting parameters are usually normal unless the DIC is fulminating. It is usually thought that fibrinogen may be low or absent in DIC. However, afibrinogenemia is rare. Fibrinogen is usually high...

Journal: :Acta biochimica Polonica 2012
Zeynep M Eskici Şerefden Açıkgöz Nihal Pişkin Görkem Mungan Murat Can Berrak Güven Fürüzan Köktürk

Cytokines trigger coagulant and fibrinolytic systems in sepsis to result in Disseminated Intravascular Coagulation (DIC) that is an important complication and leads to disseminated hemorrhages and multi-organ failure. High Mobility Group B1 DNA Binding (HMGB1) protein is a cytokine taking part in systemic inflammatory response. The objective of this study was to investigate HMGB1 levels in grou...

Journal: :Onkologie 2006
Marc Roger Schlaeppi Wolfgang Korte Roger von Moos Thomas Cerny Silke Gillessen

BACKGROUND Acute disseminated intravascular coagulation (DIC) in cancer is rare and often fatal, whereas chronic forms are more frequent. CASE REPORT A 37-year-old man with a known history of melanoma excised 6 years ago, presented with abdominal pain, fatigue and epistaxis. A computed tomography scan revealed diffuse metastatic disease of the liver, and laboratory analysis was consistent wit...

Journal: :Veterinary clinical pathology 2007
Jennifer L Brazzell Dori L Borjesson

BACKGROUND Current coagulation tests lack sensitivity and detect disseminated intravascular coagulation (DIC) only when it is severe. Measurement of antithrombin (AT) activity and D-dimer concentration permits early diagnosis and more precise classification of coagulopathies in some species. OBJECTIVES The objectives of this study were to validate and determine the diagnostic utility of a chr...

2015
Shuai Shi Zhaoliang Zhang Zichao Luo Jing Yu Renlong Liang Xingyi Li Hao Chen

This study aimed to develop a cationic nanosuspension of chitosan (CS) and methoxy poly(ethylene glycol)-poly(ε-caprolactone) (MPEG-PCL) for ocular delivery of diclofenac (DIC). MPEG-PCL-CS block polymer was synthesized by covalent coupling of MPEG-PCL with CS. The critical micelle concentration of the MPEG-PCL-CS block polymer was 0.000692 g/L. DIC/MPEG-PCL-CS nanosuspension (mean particle siz...

2018
Yuichi Miyashima Masaya Iwamuro Michihiko Shibata Yoshio Miyabe Yoshinari Kawai Masanobu Kaihara Takehide Mitogawa Masaru Harada

Objective Cases of Japanese spotted fever (JSF) are sometimes complicated by disseminated intravascular coagulation (DIC) with an abnormal liver function, resulting in unfavorable outcomes. The aim of the present study was to clarify the correlation between liver function test results and DIC scores. Methods Twenty patients diagnosed with JSF between April 2010 and April 2014 were enrolled. Age...

Journal: :Blood 1985
R A Marlar J Endres-Brooks C Miller

This study was undertaken to determine the levels of protein C antigen and activity and protein C inhibitor in sequential plasma samples of disseminated intravascular coagulation (DIC) patients. Our normal range for both protein C antigen and activity is 70 to 130 U/dL, and protein C inhibitor is 65 to 135 U/dL. A decreased level of protein C activity was found in 96% of the plasma samples from...

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