In vivo, leukocyte transendothelial migration (TEM) occurs at endothelial cell junctions (paracellular) and nonjunctional (transcellular) locations, whereas in vitro models report that TEM is mostly paracellular. The mechanisms that control the route of leukocyte TEM remain unknown. Here we tested the hypothesis that elevated intercellular adhesion molecule-1 (ICAM-1) expression regulates the l...

BACKGROUND AND STUDY AIMS Large ( > 2 cm) rectal adenomas are currently treated by either transanal endoscopic microsurgery (TEM) or piecemeal endoscopic mucosal resection (EMR). The potential lower morbidity of EMR may become irrelevant if EMR is less effective. The aim of this study was to compare the safety and effectiveness of EMR and TEM for large rectal adenomas. PATIENTS AND METHODS A ...

TEM images are rapidly gaining prominence in various sectors like life sciences, pathology, medical science, semiconductors, forensics, etc. Hence, there is a critical need to know the effect of existing image restoration and enhancement techniques available for TEM images. This paper primarily focuses on DVROFT filter. After simulation it is observed that the SNR and PSNR ratios obtained for T...

BACKGROUND & OBJECTIVE Extended-spectrum beta-lactamases (ESBLs) are rapidly evolving group of beta-lactamase enzymes produced by the Gram negative bacteria. These enzymes have been derived from TEM and SHV genes by mutations and have been well described in Klebsiella pneumoniae. Information on molecular types of ESBL positive Klebsiella sp. is lacking from India. We therefore undertook this st...

Researchers have used transmission electron microscopy (TEM) to make contributions to cell biology for well over 50 years, and TEM continues to be an important technology in our field. We briefly present for the neophyte the components of a TEM-based study, beginning with sample preparation through imaging of the samples. We point out the limitations of TEM and issues to be considered during ex...

The role of human bone marrow (BM) CD8+ T cells in the immune response to viral Ags is poorly defined. We report here the identification and characterization of a functionally enhanced effector memory CD8+ T cell population (TEM) in the BM of patients undergoing total joint replacement for osteoarthritis. These BM-derived TEM differ strikingly from correlate cells in peripheral blood (PB), expr...

In transmission electron microscopy (TEM) for biological and polymer samples, it is difficult to image with high contrast, since they are mostly composed of light elements and have similar density. One solution to enhance the contrast is utilization of phase contrast microscopy, which is realized in optical microscopy. Accordingly, many types of phase plates for electron microscopy have been pr...

The clinical strain Escherichia coli TO799 was resistant to penicillin-clavulanate combinations and ceftazi-dime and was not reproducibly detected as an extended-spectrum ␤-lactamase (ESBL) according to the standards of the Clinical Laboratory Standards Institute (CLSI; formerly NCCLS) and the national guidelines of the French Society for Microbiology (Comité de l'Antibiogramme de la Société Fr...

This paper discusses automatic Transmission Electron Microscopy (TEM) image registration, TEM slice assembly via tile mosaicking, and TEM volume assembly via slice to slice registration. Several algorithms are presented, including an algorithm for mosaic layout of an unordered set of tiles, an algorithm for distortion correction, and an image processing algorithm for a coarse edge and blob dete...