The cyclic peptide core of the antifungal and antibiotic cyclic depsipeptide LI-F04a was synthesised by using a modified Yamaguchi macrolactonization approach. Alternative methods of macrolactonization (e.g., Corey-Nicolaou) resulted in significant epimerization of the C-terminal amino acid during the cyclization reaction. The D-stereochemistry of the alanine residue in the naturally occurring ...

At the previous OSDI, Silas Boyd-Wickizer presented Corey, a new many-core operating system motivated by the premise that traditional OS design, as represented by Linux, faced fundamental limitations to scalability. This talk, also given by Boyd-Wickizer, refutes that premise. It does so by selecting several real applications with good parallel implementations that demonstrate kernel-based scal...

با توجه به رشد بالای جمعیت در جهان و نیاز اطمینان از امنیت غذایی، افزایش تولید واحد سطح محصولات زراعی به‌منزلة راهبردی اساسی حل مسئلة تأمین غذا به‌شمار می‌رود. سوی دیگر، وجود محدودیت زیرکشت پایین‌بودن میانگین عملکرد برخی کشاورزی مانند گندم کشور، محصول می‌تواند راهکاری عملی پاسخ کشور محسوب شود. یکی مهم‌ترین بیماری‌های فوزاریوم است که، نقش پیش‌بینی این بیماری جلوگیری کاهش بهره‌وری محصول، مدل‌هایی...

The Prevalence of Rheumatic Heart Disease in Western Kenya: An Echocardiographic Study by Thomas Holland Duke Global Health Institute Duke University Date:_______________________ Approved: ___________________________ Christopher Woods, Supervisor ___________________________ G. Ralph Corey ___________________________ Nathan Thielman An abstract of a thesis submitted in partial fulfillment of the...

Prasanta Pal, Jerzy Blawzdziewicz, and Corey S. O’Hern 4, 5 1 Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, 06520-8042 Department of Mechanical Engineering, Texas Tech University, Lubbock, TX 79409-1021 Department of Mechanical Engineering & Materials Science, Yale University, New Haven, CT 06520-8286 Department of Applied Physics, Yale University, New H...

Corey M. Johnson is Head, Library Instruction, in the Holland Library at Washington State University; e-mail: [email protected]. Carol M. Anelli is Professor of Entomology in Food Nutrition Library at Washington State University; e-mail: [email protected]. Betty J. Galbraith is Science Librarian and Instruction Coordinator in Owen Library at Washington State University; e-mail: [email protected]. ...

A comparison of Standard Galerkin, Petrov–Galerkin, and Fully-Upwind Galerkin methods for the simulation of two-phase flow in heterogeneous porous media is presented. On the basis of the coupled pressure–saturation equations, a generalized formulation for all three finite element methods is derived and analysed. For flow in homogeneous media, the Petrov–Galerkin method gives excellent results. ...

Most engineering infrastructures, including municipal solid waste containment facilities, are situated in unsaturated zone. The use of chemical additives for soil improvement has been linked to the adverse environmental issues being experienced globally. Research into more sustainable methods led discovery a novel and innovative method known as microbial induced calcite precipitation (MICP). La...