OBJECTIVES A recent randomized study showed switch maintenance with pemetrexed after nonpemetrexed-containing first-line chemotherapy in patients with advanced nonsmall-cell lung cancer to prolong overall survival by 2.8 months. We examined the cost-effectiveness of pemetrexed in this indication, from the perspective of the Swiss health care system, and assessed the influence of the costs of be...

We present and demonstrate a multi-criteria approach for evaluating R&D projects in different stages of their life cycle. Our approach integrates the balanced scorecard (BSC) and data envelopment analysis (DEA) and develops an extended DEA model. The input and output measures for the integrated DEA–BSC model are grouped in “cards” which are associated with a “BSC for R&D projects”. The BSC is e...

Basosquamous carcinoma (BsC) is a controversial entity and both a diagnostic and therapeutic challenge. BsC has mixed histopathological characteristics of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). BCC and SCC display characteristic histopathology and behaviour; on the other hand, BsC is a rare tumour, which has variable morphology and displays less predictable behaviour...

Article Type Research Article Authors Fahimi Manzari Sh.1 BSc, Askarramaki Sh.* BSc, Sam Sh.2 PhD, Pourghasem M.3 PhD

Abstract. One of the challenges in studying desert dust aerosol along with its numerous interactions and impacts is paucity direct situ measurements, particularly areas most affected by storms. Satellites typically provide column-integrated but observationally constrained continuous 3D fields are needed to assess variability, climate effects upon a variety socio-economic sectors. Here, we prese...

Morphological and physiological characteristics of biological soil crusts (BSCs) enhance soil stability and fertility, and influence soil chemistry. However, the effect of BSCs on soil physico-chemical properties may vary depending on taxa (cyanobacteria, lichen, bryophytes) and species, and be susceptible to soil surface disturbance. We examined a wide variety of soil physico-chemical properti...

Cedric Manlhiot, BSc; Ines B. Menjak, MD; Leonardo R. Brandão, MD; Colleen E. Gruenwald, RN CCP, PhD; Steven M. Schwartz, MD; V. Ben Sivarajan, MD; Hyaemin Yoon, MD; Robert Maratta, MSc; Caitlin L. Carew, MSc; Janet A. McMullen, BSc; Nadia A. Clarizia, BSc; Helen M. Holtby, MB, BS; Suzan Williams, MD; Christopher A. Caldarone, MD; Glen S. Van Arsdell, MD; Anthony K. Chan, MD; Brian W. McCrindle...

Eszter Dombi, BSc Alan Diot, PhD Karl Morten, PhD Janet Carver, BSc Tiffany Lodge, BSc Carl Fratter, FRCPath Yi Shiau Ng, MRCP Chunyan Liao, PhD Rebecca Muir Emma L. Blakely, PhD, FRCPath Iain Hargreaves, PhD Mazhor Al-Dosary, PhD Gopa Sarkar, MRCPCH Simon J. Hickman, PhD, FRCP Susan M. Downes, MD Sandeep Jayawant, FRCPCH Patrick Yu-Wai-Man, PhD, FRCOphth Robert W. Taylor, PhD, FRCPath Joanna P...

author team: Michel d. landry Pt, Phd; Mandy McGlynn BSc Pt, MSc; edith ng ot reg. (ont); angie andreoli BSc (Pt), MSc; tess devji ot reg. (ont); Cheryl Bower Mn rn(eC); anita Goyal, ot reg. (ont); Sylvia Haycock ot reg. (ont); Jamie a. Young Pt; diane leber rn, etn, BScn; Kristina Guy Pt, BSc(HK), BScPt, MSc(c); anita Vanderwerf rn; Jackie Wright rn, BScn; Suzanne iafolla MPt; ian M. Horne rn,...