Co-Simulation is a general approach to simulate coupled technical systems. In a master-slave concept the slaves simulate sub-problems whereas the master is responsible for both coordinating the overall simulation as well as transferring data. To unify the interface between master and slave the FMI for CoSimulation was developed. Using FMI a master was implemented with simple and advanced algori...

El neoliberalismo implicó, desde la década de los setenta, una profunda reconfiguración las economías nacionales y un aumento significativo desigualdades. Fondo Monetario Internacional (FMI), que se autopercibe por encima derechos humanos, ha sido vehículo institucional central en este cambio, a través sus créditos condicionalidades frecuentemente traducen violaciones humanos poblaciones Estado...

Silvia Arber Biozentrum and FMI, Basel, Switzerland Silvia Arber is a Professor of Neurobiology at the Biozentrum of the University of Basel and aSenior Investigator at the Friedrich Miescher Institute (FMI) for Biomedical Research in Basel, Switzerland. Her laboratory investigates neuronal circuits controlling motor behavior. Current work aims to uncover the synaptic organization of motor circ...

During development, multiple environmental cues, e.g., growth factors, cell adhesion molecules, etc., interact to influence the pattern of outgrowth of axons and dendrites in a cell-specific fashion. As a result, individual neurons may receive similar signals, but make unique choices, leading to distinct wiring within the nervous system. C. elegans has been useful in identifying molecular cues ...

Accurate measurement of fat mass has become increasingly important with the increasing incidence of obesity. We assessed fat and muscle mass of Koreans with the Korea National Health and Nutrition Examination Survey IV (KNHANES IV). We studied 10,456 subjects (aged 20 to 85 yr; 4,476 men, 5,980 women). Fat and muscle mass were measured by dual-energy x-ray absorptiometry. Reference values of bo...

The Drosophila wing provides an appropriate model system for studying genetic programming of planar cell polarity (PCP) [1-4]. Each wing cell respects the proximodistal (PD) axis; i.e., it localizes an assembly of actin bundles to its distalmost vertex and produces a single prehair. This PD polarization requires the redistribution of Flamingo (Fmi), a seven-pass transmembrane cadherin, to proxi...

Esta investigación estima el peso de los sobrecargos que Fondo Monetario Internacional (FMI) espera cobrar a países deudores medianos ingresos durante 2023-2033. La evidencia indica no logran su supuesto objetivo incentivar pago anticipado las deudas; en cambio, incrementan la deuda prestatarios precisamente enfrentan problemas más graves balanza pago, mientras FMI se beneficia estas crisis.

Previous studies suggest a relationship between systemic inflammation and body composition in chronic obstructive pulmonary disease (COPD). We examined the relationships between body composition (fat free mass index (FFMI) kg·m(-2) and fat mass index (FMI) kg·m(-2)) and three plasma inflammatory markers C-reactive Protein (CRP), soluble tumour necrosis factor receptor 1 (sTNF-R1) and osteoprote...

In addition to apicobasal polarization, some epithelia also display polarity within the plane of the epithelium. To what extent polarized endocytosis plays a role in the establishment and maintenance of planar cell polarity (PCP) is at present unclear. Here, we investigated the role of Rabenosyn-5 (Rbsn-5), an evolutionarily conserved effector of the small GTPase Rab5, in the development of Dro...

Photoreceptors (R cells) in the Drosophila retina connect to targets in three distinct layers of the optic lobe of the brain: R1-R6 connect to the lamina, and R7 and R8 connect to distinct layers in the medulla. In each of these layers, R axon termini are arranged in evenly spaced topographic arrays. In a genetic screen for mutants with abnormal R cell connectivity, we recovered mutations in fl...