The NMDA and AMPA classes of ionotropic glutamate receptors are concentrated at postsynaptic sites in excitatory synapses. NMDA receptors interact via their NR2 subunits with PSD-95/SAP90 family proteins, whereas AMPA receptors bind via their GluR2/3 subunits to glutamate receptor-interacting protein (GRIP), AMPA receptor-binding protein (ABP), and protein interacting with C kinase 1 (PICK1). W...

conclusions the taping technique, as applied in this study demonstrates an impressive effect on wrist extension force and grip strength of patients with te. elbow taping also reduces pain at the lateral aspect of the elbow in these patients. background tennis elbow (te) is a common musculotendinous degenerative disorder of the extensor origin at the lateral humeral epicondyle. different modes o...

The North Atlantic INTIMATE group of the INQUA Palaeoclimate Commission has previously recommended an Event Stratigraphy approach for the synchronisation of records of the Last Termination using the Greenland GRIP isotopic record as the regional stratotype and INTCAL98 for the calibration of radiocarbon dates [Lowe, J.J., Hoek, W., INTIMATE Group, 2001. Inter-regional correlation of palaeoclima...

Object manipulation requires rapid increase in grip force to prevent slippage when the load force of the object suddenly increases. Previous experiments have shown that grip force reactions interact between the hands when holding a single object. Here we test whether this interaction is modulated by the object dynamics experienced before the perturbation of the load force. We hypothesized that ...

BACKGROUND Poor grip strength is an indicator of frailty and a precursor to functional limitations. Although poor grip strength is more prevalent in older disabled African American women, little is known about the association between race and poverty-related disparities and grip strength in middle-aged men and women. METHODS We examined the cross-sectional relationship between race, socioecon...

Anticipatory grip force adjustments are a prime example of the predictive nature of motor control. An object held in precision grip is stabilized by fine adjustments of the grip force against changes in tangential load force arising from inertia during acceleration and deceleration. When an object is subject to sudden impact loads, prediction becomes critical as the time available for sensory f...

Numerous studies have investigated the kinematics of arm movements; others have examined grip forces during static holding of objects. However, the coordination of grip force and arm movement when moving grasped objects has not been documented. We show that grip force is finely modulated in phase with load force during movements with grasped objects in which load force varies with acceleration....

OBJECTIVES We assessed whether grip strength was related to various types of radiographic damage in Korean adults with osteoarthritis (OA). METHODS Data from 2,251 subjects enrolled in the Dong-gu study, who had no hand joint pain, were analyzed to investigate the relationship between grip strength and OA. Hand grip strength was measured using a hand-held dynamometer, and radiographs of the h...