AIMS To investigate the immunocytochemical expression of the tissue specific transcription factor-1 (TTF-1) on cytological specimens of small cell lung carcinoma (SCLC) and to establish its value in the cytological diagnosis of lung cancer. METHODS For each case, the diagnosis was made on cytological specimens and confirmed on subsequent bronchial biopsy specimens. TTF-1 was detected immunocy...

The nuclear immunoreactivity for thyroid transcription factor-1 (TTF-1) is a useful marker for identification of carcinomas of thyroid and lung origin. Our aim was to determine whether cytoplasmic staining in the liver is a result of cross-reaction of anti-TTF-1 antibody (clone 8G7G3/1, DAKO, Carpinteria, CA) or true positivity resulting from aberrant expression of TTF-1 or products of the alte...

Thyroid transcription factor gene 1 (TTF-1) is a homeobox-containing gene involved in thyroid organogenesis. During early thyroid development, the homeobox gene Nkx-2.5 is expressed in thyroid precursor cells coincident with the appearance of TTF-1. The aim of this study was to investigate the molecular mechanisms underlying thyroid-specific gene expression. We show that the Nkx-2.5 C terminus ...

A TTF-triple (C, T , F) in an abelian category is one-sided split in case either (C, T) or (T , F) is a split torsion theory. In this paper we classify one-sided split TTF-triples in module categories, thus completing Jans' classification of two-sided split TTF-triples and answering a question that has remained open for almost forty years.

Organic conductors exhibit unusual physical properties due to the critical nature of valence electrons fluctuating under localizing and delocalizing regime. Recently, we discovered that an organic superconductor, α-(BEDT-TTF)2I3 [BEDTTTF: bis(ethylenedithio)tetrathiafulvalene], induces optical second-harmonic generation (SHG) along with charge-ordering driven by the repulsive electron-electron ...

Many organic metals display exotic properties such as superconductivity, spin-charge separation and so on and have been described as quasi-one-dimensional Luttinger liquids. However, a genuine Fermi liquid behaviour with quasiparticles and Fermi surfaces have not been reported to date for any organic metal. Here, we report the experimental Fermi surface and band structure of an organic metal (B...

In electronic-type ferroelectrics, where dipole moments produced by the variations of electron configurations are aligned, the polarization is expected to be rapidly controlled by electric fields. Such a feature can be used for high-speed electric-switching and memory devices. Electronic-type ferroelectrics include charge degrees of freedom, so that they are sometimes conductive, complicating d...

The crystal structures, thin-film properties, and field-effect transistor (FET) characteristics of tetrathiafulvalene (TTF) derivatives with two phenyl groups are systematically investigated. The highest mobility, 0.11 cm(2) V(-1) s(-1), is observed in biphenyl-substituted TTF (1). The correlation between the crystal structures and the FET properties demonstrates that good transistor properties...

Prior research on Task Technology Fit Theory (TTF) has found that task experience does not moderate perceptions of tasktechnology fit and does not directly affect technology usage. Additionally, researchers using TTF must develop new items to operationalize TTF constructs for each study. This study will reexamine the role of task experience in TTF within the context of systems development metho...

Background: Thyroid transcription factor-1 (TTF-1) is expressed in approximately 70% of lung adenocarcinomas and one the most reliable makers to distinguish primary adenocarcinoma from metastatic disease. TTF-1-negative status a poor prognostic factor, associated with efficacy immune checkpoint inhibitor (ICI) monotherapy. However, relationship between TTF-1 expression ICI plus chemotherapy sti...