PURPOSE Postinfectiously irritable bowel syndrome (PI-IBS) develops in 3-30% of individuals with bacterial gastroenteritis. Recent studies demonstrated increases in inflammatory components in gut mucosa of PI-IBS patients even after complete resolution of infection. We aimed to investigate histological changes in colon and rectum of PI-IBS subjects after long term period of infection. MATERIA...

Blastocystis is a protistan parasite living in the digestive tract of many animals, including humans. This highly prevalent intestinal parasite is suspected to be linked to Irritable Bowel Syndrome (IBS), a chronic functional bowel disorder. Here, we first compared the prevalence of Blastocystis among 56 IBS patients (40 IBS with constipation (IBS-C), 9 IBS with diarrhea (IBS-D), 4 mixed IBS (I...

Irritable bowel syndrome (IBS) is a chronic functional disorder and its development may be linked, directly and indirectly, to intestinal dysbiosis. Here we investigated the interactions between IBS symptoms and the gut microbiome, including the relation to rifaximin (1200 mg daily; 11.2 g per a treatment). We recruited 72 patients, including 31 with IBS-D (diarrhea), 11 with IBS-C (constipatio...

Until now, Irritable Bowel Syndrome (IBS) has been one of gastrointestinal disorders which have not been fully understood. Clinically, there are some findings that indicate the role of inflammatory process in pathogenesis of IBS; such as, the onset of IBS that occurs after an episode of gastroenteritis (post-infective IBS (PI-IBS)). Although there is less evidence supporting genetic factors in ...

Introduction and purpose of the work: Irritable Bowel Syndrome (IBS) affects up to 10% population. The deterioration in health-related quality life IBS patients has been shown be comparable to, perhaps even more severe than, other serious chronic organic diseases such as inflammatory bowel disease, diabetes, hypertension, end-stage renal disease. aim study is present a new method treatment.Stat...

Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the "nonsterile" developing world environm...

BACKGROUND Abdominal bloating is a common symptom in patients with irritable bowel syndrome with constipation (IBS-C). However, it is not included among the required items in the Rome III diagnostic criteria for IBS. Little is known about an impact of abdominal bloating seen in patients with IBS-C. Using a large population-based sample, the aim of the present study was to investigate what is th...

OBJECTIVE Previous studies have shown that up to 50% to 70% of patients with irritable bowel syndrome (IBS) who seek treatment have psychiatric comorbidity. The aim of this study was to report the history of anxiety and depression in IBS patients. METHODS The study, designed as a cross-sectional, was performed in a consecutive sample of individuals diagnosed with IBS in the Gastroenterology C...

BACKGROUND Both psychological and physiological disturbances have been implicated in the aetiopathogenesis of irritable bowel syndrome (IBS). AIMS To investigate how the psychological factors act, and the involvement of infective and physiological factors. METHODS Consecutive patients hospitalised for gastroenteritis reported life events for the previous 12 months, and past illness experien...

background: in clinical trials of irritable bowel syndrome (ibs), evaluation of treatment efficacy is still mainly subjective.we compared three outcome measures in reflecting response to treatment in a clinical trial of ibs. â  materials and methods: sixty three adult ibs patients participated in a placebo-controlled trial of 10-wk cognitive-behavioral therapy. patients completed the ibs-qualit...