OBJECTIVE To evaluate the antihyperglycemic activity of ethyl acetate extract of Hypericum perforatum (H. perforatum) in streptozotocin (STZ)-induced diabetic rats. METHODS Acute toxicity and oral glucose tolerance test were performed in normal rats. Male albino rats were rendered diabetic by STZ (40 mg/kg, intraperitoneally). H. perforatum ethyl acetate extract was orally administered to dia...

Hypericum perforatum (St John's wort) is a reservoir of diverse classes of biologically active and high value secondary metabolites, which captured the interest of both researchers and the pharmaceutical industry alike. Several studies and clinical trials have shown that H. perforatum extracts possess an astounding array of pharmacological properties. These properties include antidepressant, an...

This paper is concerned with estimating preference functionals for choice under risk from the choice behaviour of individuals. We note that there is heterogeneity in behaviour between individuals and within individuals. By ‘heterogeneity between individuals’ we mean that people are different, in terms of both their preference functionals and their parameters for these functionals. By ‘heterogen...

Science Highlights First Structural Investigation of a Super-Hydrated Zeolite Yongjae Lee,1 Thomas Vogt,1 Joseph A. Hriljac,2 John B. Parise,3 and Gilberto Artioli4 1Physics Dept, Brookhaven National Laboratory, Upton, NY 2School of Chemical Sciences, The University of Birmingham, Birmingham, UK 3Geosciences Dept, State University of New York, Stony Brook, NY 4University Milan, Dipartimento Sci...

Hyperfoliatin, a new polyisoprenylated phloroglucinol derivative was isolated from the aerial parts of Hypericum perfoliatum (Clusiaceae) collected in Algeria. The structure of hyperfoliatin was elucidated on the basis of its spectral data, mainly MS and multiple-pulse NMR.

objective: hypericum perforatum (st. john's wort) has long been used in traditional medicine to treat a variety of internal and external ailments. the present study was done to evaluate the immumodulatory potentials of the hydroalcoholic extract of h. perforatum. materials and methods: twenty male balb/c-mice were randomly allocated in two equal groups and immunized with sheep red blood ce...

over production of uric acid by xanthine oxidase (xo) causes gout. xo inhibitors for example allopurinol are the most important available anti gout drugs. medicinal herbs are available natural sources that may be useful for the treatment of gout. in this study the inhibitory activity of aqueous extracts of matricaria chamomilla l., hypericum perforatum l., fraxinus excelsior l., zea mays l., tr...